Exact and numerical solutions of a spatially-distributed mathematical model for fluid and solute transport in peritoneal dialysis (Q2412372): Difference between revisions
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Latest revision as of 03:43, 20 March 2024
scientific article
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English | Exact and numerical solutions of a spatially-distributed mathematical model for fluid and solute transport in peritoneal dialysis |
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Exact and numerical solutions of a spatially-distributed mathematical model for fluid and solute transport in peritoneal dialysis (English)
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23 October 2017
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Summary: The nonlinear mathematical model for solute and fluid transport induced by the osmotic pressure of glucose and albumin with the dependence of several parameters on the hydrostatic pressure is described. In particular, the fractional space available for macromolecules (albumin was used as a typical example) and fractional fluid void volume were assumed to be different functions of hydrostatic pressure. In order to find non-uniform steady-state solutions analytically, some mathematical restrictions on the model parameters were applied. Exact formulae (involving hypergeometric functions) for the density of fluid flux from blood to tissue and the fluid flux across tissues were constructed. In order to justify the applicability of the analytical results obtained, a wide range of numerical simulations were performed. It was found that the analytical formulae can describe with good approximation the fluid and solute transport (especially the rate of ultrafiltration) for a wide range of values of the model parameters.
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nonlinear differential equation
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fluid and solute transport
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transport in peritoneal dialysis
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steady-state solution
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hypergeometric function
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