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Multidimensional Penalized Splines for Survival and Net Survival Models
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1.5.2
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publication date: 11 September 2021
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1.0.0
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publication date: 27 February 2019
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1.0.1
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publication date: 1 March 2019
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1.1.0
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publication date: 2 May 2019
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1.2.0
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publication date: 29 August 2019
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1.3.0
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publication date: 3 February 2020
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1.5.0
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publication date: 25 May 2020
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1.5.1
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publication date: 25 September 2020
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1.6.0
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publication date: 13 September 2023
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13 September 2023
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Fits hazard and excess hazard models with multidimensional penalized splines allowing for time-dependent effects, non-linear effects and interactions between several continuous covariates. In survival and net survival analysis, in addition to modelling the effect of time (via the baseline hazard), one has often to deal with several continuous covariates and model their functional forms, their time-dependent effects, and their interactions. Model specification becomes therefore a complex problem and penalized regression splines represent an appealing solution to that problem as splines offer the required flexibility while penalization limits overfitting issues. Current implementations of penalized survival models can be slow or unstable and sometimes lack some key features like taking into account expected mortality to provide net survival and excess hazard estimates. In contrast, survPen provides an automated, fast, and stable implementation (thanks to explicit calculation of the derivatives of the likelihood) and offers a unified framework for multidimensional penalized hazard and excess hazard models. survPen may be of interest to those who 1) analyse any kind of time-to-event data: mortality, disease relapse, machinery breakdown, unemployment, etc 2) wish to describe the associated hazard and to understand which predictors impact its dynamics. See Fauvernier et al. (2019a) <doi:10.21105/joss.01434> for an overview of the package and Fauvernier et al. (2019b) <doi:10.1111/rssc.12368> for the method.
Property / description: Fits hazard and excess hazard models with multidimensional penalized splines allowing for time-dependent effects, non-linear effects and interactions between several continuous covariates. In survival and net survival analysis, in addition to modelling the effect of time (via the baseline hazard), one has often to deal with several continuous covariates and model their functional forms, their time-dependent effects, and their interactions. Model specification becomes therefore a complex problem and penalized regression splines represent an appealing solution to that problem as splines offer the required flexibility while penalization limits overfitting issues. Current implementations of penalized survival models can be slow or unstable and sometimes lack some key features like taking into account expected mortality to provide net survival and excess hazard estimates. In contrast, survPen provides an automated, fast, and stable implementation (thanks to explicit calculation of the derivatives of the likelihood) and offers a unified framework for multidimensional penalized hazard and excess hazard models. survPen may be of interest to those who 1) analyse any kind of time-to-event data: mortality, disease relapse, machinery breakdown, unemployment, etc 2) wish to describe the associated hazard and to understand which predictors impact its dynamics. See Fauvernier et al. (2019a) <doi:10.21105/joss.01434> for an overview of the package and Fauvernier et al. (2019b) <doi:10.1111/rssc.12368> for the method. / rank
 
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Property / author: Mathieu Fauvernier / rank
 
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Property / author: Laurent Roche / rank
 
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Property / author: Laurent Remontet / rank
 
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Property / copyright license: GNU General Public License, version 3.0 / rank
 
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Property / copyright license: File License / rank
 
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Property / cites work
 
Property / cites work: survPen: an R package for hazard and excess hazard modelling with multidimensional penalized splines / rank
 
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Property / cites work: Multi-Dimensional Penalized Hazard Model with Continuous Covariates: Applications for Studying Trends and Social Inequalities in Cancer Survival / rank
 
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Property / Software Heritage ID: swh:1:snp:5bf9e5de9e222e13ccf2ca35a6cb88826f6f5202 / rank
 
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point in time: 10 October 2023
Timestamp+2023-10-10T00:00:00Z
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Latest revision as of 21:56, 21 March 2024

Multidimensional Penalized Splines for Survival and Net Survival Models
Language Label Description Also known as
English
survPen
Multidimensional Penalized Splines for Survival and Net Survival Models

    Statements

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    1.5.2
    11 September 2021
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    1.0.0
    27 February 2019
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    1.0.1
    1 March 2019
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    1.1.0
    2 May 2019
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    1.2.0
    29 August 2019
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    1.3.0
    3 February 2020
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    1.5.0
    25 May 2020
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    1.5.1
    25 September 2020
    0 references
    1.6.0
    13 September 2023
    0 references
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    13 September 2023
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    Fits hazard and excess hazard models with multidimensional penalized splines allowing for time-dependent effects, non-linear effects and interactions between several continuous covariates. In survival and net survival analysis, in addition to modelling the effect of time (via the baseline hazard), one has often to deal with several continuous covariates and model their functional forms, their time-dependent effects, and their interactions. Model specification becomes therefore a complex problem and penalized regression splines represent an appealing solution to that problem as splines offer the required flexibility while penalization limits overfitting issues. Current implementations of penalized survival models can be slow or unstable and sometimes lack some key features like taking into account expected mortality to provide net survival and excess hazard estimates. In contrast, survPen provides an automated, fast, and stable implementation (thanks to explicit calculation of the derivatives of the likelihood) and offers a unified framework for multidimensional penalized hazard and excess hazard models. survPen may be of interest to those who 1) analyse any kind of time-to-event data: mortality, disease relapse, machinery breakdown, unemployment, etc 2) wish to describe the associated hazard and to understand which predictors impact its dynamics. See Fauvernier et al. (2019a) <doi:10.21105/joss.01434> for an overview of the package and Fauvernier et al. (2019b) <doi:10.1111/rssc.12368> for the method.
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