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Latest revision as of 17:13, 18 June 2024

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Some nonstandard modeling techniques in theoretical biology
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    Some nonstandard modeling techniques in theoretical biology (English)
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    1988
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    Three topics are surveyed. (1) The quasisteady-state assumption is a fundamental example of frequent instances in theoretical biology where advantage can be taken of the simultaneous existence of widely separated time scales. It is shown that appropriate scaling can provide a markedly sharper estimate of the range of validity of this approximation. (2) A new methodology for modelling dynamically changing networks is applied to simple morphogenesis in fungal colonies. A brief discussion is given of possible application to the complex polymerization and cross- linking that characterize cytoplasmic fibers. (3) It is shown that problems in ecology and immunology can be illuminated by considering nonlocal interactions (and hence integrodifferential equations) that generate patterns in ``aspect space'' or ``shape space''.
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    modeling techniques
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    review
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    enzyme kinetics
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    biochemistry
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    quasisteady- state assumption
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    time scales
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    scaling
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    modelling dynamically changing networks
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    morphogenesis in fungal colonies
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    polymerization
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    cross- linking
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    cytoplasmic fibers
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    immunology
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    nonlocal interactions
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    integrodifferential equations
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