Local alignment of Markov chains (Q862205): Difference between revisions

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Latest revision as of 13:43, 25 June 2024

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Local alignment of Markov chains
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    Local alignment of Markov chains (English)
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    5 February 2007
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    This paper investigates local alignments without gaps of two independent Markov chains from a finite alphabet. Sufficient conditions are established for the number of essentially different local alignments with a score exceeding a high threshold to be asymptotically Poisson distributed. From the Poisson approximation a Gumbel approximation of the maximal local alignment score is obtained. The results extend known results for independent sequences of i.i.d random variables.
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    Chen-Stein method
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    extreme value theory
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    large deviations
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    local alignment
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    Markov additive processes
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    Poisson approximation
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