Rational tangle surgery and Xer recombination on catenanes (Q441066): Difference between revisions
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Property / DOI: 10.2140/agt.2012.12.1183 / rank | |||
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There are several biological experiments where through recombination the knot type of circular DNA is changed. Here the authors concentrate on experiments where through a recombinase called Xer a \((2,2k)\)-torus link was changed to a knot with \(2k+1\) crossings. The mathematical model used here is an extension of the tangle model introduced by \textit{C. Ernst} and \textit{D. W. Sumners} [Math. Proc. Camb. Philos. Soc. 108, No. 3, 489--515 (1990; Zbl 0727.57005)]. The action of recombinase converting one knot into another is modelled either by tangle surgery or in the specific case here by band surgery. Band surgery is a special case of tangle surgery, namely replacing the \(0\)-tangle by a \((1/w)\)-tangle for some integer \(w\). In this paper band surgeries on the family of 2-bridge knots given by \(N(\frac{4mn-1}{2m})\) (where \(m, n\) are integers) yielding a \((2,2k)\)-torus link are characterized. The \(N(\frac{4mn-1}{2m})\) family of 2-bridge knots includes all the twist knots which frequently occur in biological reactions. The methods make use of earlier work by some of the authors on analysis of DNA recombination experiments [\textit{I. K. Darcy}, J. Knot Theory Ramifications 14, No. 8, 993--1005 (2005; Zbl 1090.57004)] and [\textit{M. Hirasawa} and \textit{K. Shimokawa}, Proc. Am. Math. Soc. 128, No. 11, 3445--3451 (2000; Zbl 0962.57011)]. | |||
Property / review text: There are several biological experiments where through recombination the knot type of circular DNA is changed. Here the authors concentrate on experiments where through a recombinase called Xer a \((2,2k)\)-torus link was changed to a knot with \(2k+1\) crossings. The mathematical model used here is an extension of the tangle model introduced by \textit{C. Ernst} and \textit{D. W. Sumners} [Math. Proc. Camb. Philos. Soc. 108, No. 3, 489--515 (1990; Zbl 0727.57005)]. The action of recombinase converting one knot into another is modelled either by tangle surgery or in the specific case here by band surgery. Band surgery is a special case of tangle surgery, namely replacing the \(0\)-tangle by a \((1/w)\)-tangle for some integer \(w\). In this paper band surgeries on the family of 2-bridge knots given by \(N(\frac{4mn-1}{2m})\) (where \(m, n\) are integers) yielding a \((2,2k)\)-torus link are characterized. The \(N(\frac{4mn-1}{2m})\) family of 2-bridge knots includes all the twist knots which frequently occur in biological reactions. The methods make use of earlier work by some of the authors on analysis of DNA recombination experiments [\textit{I. K. Darcy}, J. Knot Theory Ramifications 14, No. 8, 993--1005 (2005; Zbl 1090.57004)] and [\textit{M. Hirasawa} and \textit{K. Shimokawa}, Proc. Am. Math. Soc. 128, No. 11, 3445--3451 (2000; Zbl 0962.57011)]. / rank | |||
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Property / reviewed by: Claus Ernst / rank | |||
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Property / Mathematics Subject Classification ID | |||
Property / Mathematics Subject Classification ID: 57M25 / rank | |||
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Property / Mathematics Subject Classification ID | |||
Property / Mathematics Subject Classification ID: 92C40 / rank | |||
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Property / zbMATH DE Number | |||
Property / zbMATH DE Number: 6068593 / rank | |||
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Property / zbMATH Keywords | |||
tangle surgery | |||
Property / zbMATH Keywords: tangle surgery / rank | |||
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band surgery | |||
Property / zbMATH Keywords: band surgery / rank | |||
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rational tangle | |||
Property / zbMATH Keywords: rational tangle / rank | |||
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2-bridge knot | |||
Property / zbMATH Keywords: 2-bridge knot / rank | |||
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\((2,2k)\)-torus link | |||
Property / zbMATH Keywords: \((2,2k)\)-torus link / rank | |||
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tangle model of DNA recombination | |||
Property / zbMATH Keywords: tangle model of DNA recombination / rank | |||
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Property / zbMATH Keywords | |||
site specific recombination of DNA molecules | |||
Property / zbMATH Keywords: site specific recombination of DNA molecules / rank | |||
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Property / zbMATH Keywords | |||
Xer recombination | |||
Property / zbMATH Keywords: Xer recombination / rank | |||
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Property / describes a project that uses | |||
Property / describes a project that uses: TopoICE / rank | |||
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Property / MaRDI profile type: Publication / rank | |||
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Property / OpenAlex ID | |||
Property / OpenAlex ID: W2052029150 / rank | |||
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Property / arXiv ID | |||
Property / arXiv ID: 1108.0724 / rank | |||
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Property / cites work | |||
Property / cites work: Tangle solutions for a family of DNA-rearranging proteins / rank | |||
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Property / cites work: Q5601331 / rank | |||
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links / mardi / name | links / mardi / name | ||
Latest revision as of 17:45, 9 December 2024
scientific article
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English | Rational tangle surgery and Xer recombination on catenanes |
scientific article |
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Rational tangle surgery and Xer recombination on catenanes (English)
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20 August 2012
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There are several biological experiments where through recombination the knot type of circular DNA is changed. Here the authors concentrate on experiments where through a recombinase called Xer a \((2,2k)\)-torus link was changed to a knot with \(2k+1\) crossings. The mathematical model used here is an extension of the tangle model introduced by \textit{C. Ernst} and \textit{D. W. Sumners} [Math. Proc. Camb. Philos. Soc. 108, No. 3, 489--515 (1990; Zbl 0727.57005)]. The action of recombinase converting one knot into another is modelled either by tangle surgery or in the specific case here by band surgery. Band surgery is a special case of tangle surgery, namely replacing the \(0\)-tangle by a \((1/w)\)-tangle for some integer \(w\). In this paper band surgeries on the family of 2-bridge knots given by \(N(\frac{4mn-1}{2m})\) (where \(m, n\) are integers) yielding a \((2,2k)\)-torus link are characterized. The \(N(\frac{4mn-1}{2m})\) family of 2-bridge knots includes all the twist knots which frequently occur in biological reactions. The methods make use of earlier work by some of the authors on analysis of DNA recombination experiments [\textit{I. K. Darcy}, J. Knot Theory Ramifications 14, No. 8, 993--1005 (2005; Zbl 1090.57004)] and [\textit{M. Hirasawa} and \textit{K. Shimokawa}, Proc. Am. Math. Soc. 128, No. 11, 3445--3451 (2000; Zbl 0962.57011)].
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tangle surgery
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band surgery
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rational tangle
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2-bridge knot
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\((2,2k)\)-torus link
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tangle model of DNA recombination
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site specific recombination of DNA molecules
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Xer recombination
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