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27 January 2023
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Property / author: Kaspar Rufibach / rank
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Property / cites work: Joint modeling of progression‐free and overall survival and computation of correlation measures / rank
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0.1.0
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publication date: 11 December 2023
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11 December 2023
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Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.
Property / description: Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated. / rank
 
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Property / author: Holger Löwe / rank
 
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Latest revision as of 18:56, 12 March 2024

Simulating Oncology Trials using an Illness-Death Model
Language Label Description Also known as
English
simIDM
Simulating Oncology Trials using an Illness-Death Model

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    0.0.5
    27 January 2023
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    0.1.0
    11 December 2023
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    11 December 2023
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    Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.
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