mmrm (Q84387): Difference between revisions

← Older edit

@@ Property / last update @@
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Timezone +00:00
Calendar Gregorian
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@@ Property / cites work @@
-Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data
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@@ Property / cites work @@
-Recommendations for the Primary Analysis of Continuous Endpoints in Longitudinal Clinical Trials
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+Mixed models for repeated measures (MMRM) are a popular    choice for analyzing longitudinal continuous outcomes in randomized    clinical trials and beyond; see Cnaan, Laird and Slasor (1997)    <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E>    for a tutorial and Mallinckrodt, Lane, Schnell, Peng and Mancuso    (2008) <doi:10.1177/009286150804200402> for a review. This package    implements MMRM based on the marginal linear model without random    effects using Template Model Builder ('TMB') which enables fast and    robust model fitting. Users can specify a variety of covariance    matrices, weight observations, fit models with restricted or standard    maximum likelihood inference, perform hypothesis testing with    Satterthwaite or Kenward-Roger adjustment, and extract least square    means estimates by using 'emmeans'.
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@@ Property / cites work @@
+Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data
+Normal rank
@@ Property / cites work @@
+Recommendations for the Primary Analysis of Continuous Endpoints in Longitudinal Clinical Trials
+Normal rank
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@@ Property / depends on software: R / rank @@
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@@ links / mardi / name / links / mardi / name @@
+Software:84387

Latest revision as of 18:56, 12 March 2024

Mixed Models for Repeated Measures

Language	Label	Description	Also known as
English	mmrm	Mixed Models for Repeated Measures

Statements

instance of

R package

0 references

software version identifier

0.2.2

publication date

20 December 2022

0 references

0.1.3

publication date

18 October 2022

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0.1.5

publication date

18 October 2022

0 references

0.3.6

publication date

17 November 2023

0 references

0.3.7

publication date

9 December 2023

0 references

0.3.8

publication date

24 January 2024

0 references

0.3.9

publication date

25 January 2024

0 references

0.3.10

publication date

26 January 2024

0 references

0 references

0 references

26 January 2024

0 references

description

Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see Cnaan, Laird and Slasor (1997) <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E> for a tutorial and Mallinckrodt, Lane, Schnell, Peng and Mancuso (2008) <doi:10.1177/009286150804200402> for a review. This package implements MMRM based on the marginal linear model without random effects using Template Model Builder ('TMB') which enables fast and robust model fitting. Users can specify a variety of covariance matrices, weight observations, fit models with restricted or standard maximum likelihood inference, perform hypothesis testing with Satterthwaite or Kenward-Roger adjustment, and extract least square means estimates by using 'emmeans'.

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