mmrm (Q84387): Difference between revisions
From MaRDI portal
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Property / last update: 20 December 2022 / rank | |||||||||||||||
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Property / cites work: Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data / rank | |||||||||||||||
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Property / cites work: Recommendations for the Primary Analysis of Continuous Endpoints in Longitudinal Clinical Trials / rank | |||||||||||||||
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publication date: 18 October 2022
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publication date: 18 October 2022
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publication date: 17 November 2023
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publication date: 9 December 2023
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publication date: 24 January 2024
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publication date: 25 January 2024
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publication date: 26 January 2024
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26 January 2024
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Property / last update: 26 January 2024 / rank | |||||||||||||||
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Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see Cnaan, Laird and Slasor (1997) <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E> for a tutorial and Mallinckrodt, Lane, Schnell, Peng and Mancuso (2008) <doi:10.1177/009286150804200402> for a review. This package implements MMRM based on the marginal linear model without random effects using Template Model Builder ('TMB') which enables fast and robust model fitting. Users can specify a variety of covariance matrices, weight observations, fit models with restricted or standard maximum likelihood inference, perform hypothesis testing with Satterthwaite or Kenward-Roger adjustment, and extract least square means estimates by using 'emmeans'. | |||||||||||||||
Property / description: Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see Cnaan, Laird and Slasor (1997) <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E> for a tutorial and Mallinckrodt, Lane, Schnell, Peng and Mancuso (2008) <doi:10.1177/009286150804200402> for a review. This package implements MMRM based on the marginal linear model without random effects using Template Model Builder ('TMB') which enables fast and robust model fitting. Users can specify a variety of covariance matrices, weight observations, fit models with restricted or standard maximum likelihood inference, perform hypothesis testing with Satterthwaite or Kenward-Roger adjustment, and extract least square means estimates by using 'emmeans'. / rank | |||||||||||||||
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Property / author: Daniel Sabanes Bove / rank | |||||||||||||||
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Property / author: Daniel Leibovitz / rank | |||||||||||||||
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Property / author: Daniel D. Sjoberg / rank | |||||||||||||||
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Property / copyright license: Apache License, Version 2.0 / rank | |||||||||||||||
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software version identifier: ≥ 2.0 | |||||||||||||||
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software version identifier: ≥ 1.9.1 | |||||||||||||||
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Property / cites work: Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data / rank | |||||||||||||||
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Property / cites work: Recommendations for the Primary Analysis of Continuous Endpoints in Longitudinal Clinical Trials / rank | |||||||||||||||
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software version identifier: ≥ 4.0 | |||||||||||||||
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links / mardi / name | links / mardi / name | ||||||||||||||
Latest revision as of 18:56, 12 March 2024
Mixed Models for Repeated Measures
Language | Label | Description | Also known as |
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English | mmrm |
Mixed Models for Repeated Measures |
Statements
26 January 2024
0 references
Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see Cnaan, Laird and Slasor (1997) <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E> for a tutorial and Mallinckrodt, Lane, Schnell, Peng and Mancuso (2008) <doi:10.1177/009286150804200402> for a review. This package implements MMRM based on the marginal linear model without random effects using Template Model Builder ('TMB') which enables fast and robust model fitting. Users can specify a variety of covariance matrices, weight observations, fit models with restricted or standard maximum likelihood inference, perform hypothesis testing with Satterthwaite or Kenward-Roger adjustment, and extract least square means estimates by using 'emmeans'.
0 references