Optimal Bayesian design applied to logistic regression experiments (Q1116597): Difference between revisions

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Latest revision as of 23:29, 28 July 2024

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Optimal Bayesian design applied to logistic regression experiments
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    Optimal Bayesian design applied to logistic regression experiments (English)
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    1989
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    A traditional way to design a binary response experiment is to design the experiment to be most efficient for a best guess of the parameter values. A design which is optimal for a best guess however may not be efficient for parameter values close to that best guess. We propose designs which formally account for the prior uncertainty in the parameter values. A design for a situation where the best guess has substantial uncertainty attached to it is very different from a design for a situation where approximate values of the parameters are known. We derive a general theory for concave design criteria for non-linear models and then apply the theory to logistic regression. Designs found by numerical optimization are examined for a range of prior distributions and a range of criteria. The theoretical results are used to verify that the designs are indeed optimal.
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    algorithm
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    A-optimality
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    D-optimality
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    equivalence theorem
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    Nelder-Mead algorithm
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    reliability experients
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    simplex method
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    stress testing
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    binary response experiment
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    concave design criteria for non-linear models
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    logistic regression
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    numerical optimization
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