Models and approximations for random genetic drift (Q915683): Difference between revisions
From MaRDI portal
Latest revision as of 09:33, 21 June 2024
scientific article
Language | Label | Description | Also known as |
---|---|---|---|
English | Models and approximations for random genetic drift |
scientific article |
Statements
Models and approximations for random genetic drift (English)
0 references
1990
0 references
The multinomial sampling model of \textit{S. N. Ethier} and \textit{T. Nagylaki} [Adv. Appl. Probab. 12, 14-49 (1980; Zbl 0421.60062)] at a single multiallelic locus for a monoecious diploid finite population with discrete generations is considered. That model treats deterministically selection on zygotes (but not on fertility) and mutation, after which genetic drift is modelled by multinomial sampling (regulation) from an infinite population. Diffusion and other limits as \(N\to \infty\) for frequent and rare alleles are either reviewed or presented here for the first time (case of a branching process with immigration for rare alleles with allelic numbers having proper limiting distribution not concentrated at 0 when \(N\to \infty)\). Discussion and open problems follow. Limiting branching processes for the autosomal and X-linked dioecious multinomial- sampling models of Ethier and Nagylaki are also obtained (Appendix B).
0 references
limiting approximations
0 references
diffusion processes
0 references
small Gaussian fluctuations
0 references
multinomial sampling model
0 references
single multiallelic locus
0 references
monoecious diploid finite population
0 references
discrete generations
0 references
selection
0 references
zygotes
0 references
mutation
0 references
genetic drift
0 references
rare alleles
0 references
branching process with immigration
0 references
limiting distribution
0 references
0 references
0 references
0 references