Population dynamics of patients with bacterial resistance in hospital environment (Q306000): Difference between revisions

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Summary: During the past decades, the increase of antibiotic resistance has become a major concern worldwide. The researchers found that superbugs with new type of resistance genes (NDM-1) have two aspects of transmission characteristics; the first is that the antibiotic resistance genes can horizontally transfer among bacteria, and the other is that the superbugs can spread between humans through direct contact. Based on these two transmission mechanisms, we study the dynamics of population in hospital environment where superbugs exist. In this paper, we build three mathematic models to illustrate the dynamics of patients with bacterial resistance in hospital environment. The models are analyzed using stability theory of differential equations. Positive equilibrium points of the system are investigated and their stability analysis is carried out. Moreover, the numerical simulation of the proposed model is also performed which supports the theoretical findings.
Property / review text: Summary: During the past decades, the increase of antibiotic resistance has become a major concern worldwide. The researchers found that superbugs with new type of resistance genes (NDM-1) have two aspects of transmission characteristics; the first is that the antibiotic resistance genes can horizontally transfer among bacteria, and the other is that the superbugs can spread between humans through direct contact. Based on these two transmission mechanisms, we study the dynamics of population in hospital environment where superbugs exist. In this paper, we build three mathematic models to illustrate the dynamics of patients with bacterial resistance in hospital environment. The models are analyzed using stability theory of differential equations. Positive equilibrium points of the system are investigated and their stability analysis is carried out. Moreover, the numerical simulation of the proposed model is also performed which supports the theoretical findings. / rank
 
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Property / Mathematics Subject Classification ID: 92D30 / rank
 
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Property / Mathematics Subject Classification ID: 92C60 / rank
 
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Property / zbMATH DE Number: 6620805 / rank
 
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antibiotic resistance
Property / zbMATH Keywords: antibiotic resistance / rank
 
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horizontal transfer
Property / zbMATH Keywords: horizontal transfer / rank
 
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direct contact
Property / zbMATH Keywords: direct contact / rank
 
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stability analysis
Property / zbMATH Keywords: stability analysis / rank
 
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Revision as of 00:00, 28 June 2023

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Population dynamics of patients with bacterial resistance in hospital environment
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    Population dynamics of patients with bacterial resistance in hospital environment (English)
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    31 August 2016
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    Summary: During the past decades, the increase of antibiotic resistance has become a major concern worldwide. The researchers found that superbugs with new type of resistance genes (NDM-1) have two aspects of transmission characteristics; the first is that the antibiotic resistance genes can horizontally transfer among bacteria, and the other is that the superbugs can spread between humans through direct contact. Based on these two transmission mechanisms, we study the dynamics of population in hospital environment where superbugs exist. In this paper, we build three mathematic models to illustrate the dynamics of patients with bacterial resistance in hospital environment. The models are analyzed using stability theory of differential equations. Positive equilibrium points of the system are investigated and their stability analysis is carried out. Moreover, the numerical simulation of the proposed model is also performed which supports the theoretical findings.
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    antibiotic resistance
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    horizontal transfer
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    direct contact
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    stability analysis
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