Multistationarity in mass action networks with applications to ERK activation (Q455737): Difference between revisions
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In this paper, the authors establish the necessary and sufficient conditions for multistationarity that take the form of linear inequality systems in terms of the stoichiometric matrix and the reaction rate-exponent matrix. They also present a sufficient condition to identify networks where the aforementioned conditions hold. To show the applicability of the theoretical results, they analyse an ODE system that is defined by the mass action network describing the extracellular signal-regulated kinase (ERK) cascade. | |||
Property / review text: In this paper, the authors establish the necessary and sufficient conditions for multistationarity that take the form of linear inequality systems in terms of the stoichiometric matrix and the reaction rate-exponent matrix. They also present a sufficient condition to identify networks where the aforementioned conditions hold. To show the applicability of the theoretical results, they analyse an ODE system that is defined by the mass action network describing the extracellular signal-regulated kinase (ERK) cascade. / rank | |||
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Property / reviewed by | |||
Property / reviewed by: Yongli Song / rank | |||
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Property / Mathematics Subject Classification ID | |||
Property / Mathematics Subject Classification ID: 37N25 / rank | |||
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Property / Mathematics Subject Classification ID | |||
Property / Mathematics Subject Classification ID: 92C42 / rank | |||
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Property / zbMATH DE Number | |||
Property / zbMATH DE Number: 6097182 / rank | |||
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Property / zbMATH Keywords | |||
mass action kinetics | |||
Property / zbMATH Keywords: mass action kinetics / rank | |||
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Property / zbMATH Keywords | |||
multistationarity | |||
Property / zbMATH Keywords: multistationarity / rank | |||
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Property / zbMATH Keywords | |||
linear inequalities | |||
Property / zbMATH Keywords: linear inequalities / rank | |||
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Revision as of 12:32, 30 June 2023
scientific article
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English | Multistationarity in mass action networks with applications to ERK activation |
scientific article |
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Multistationarity in mass action networks with applications to ERK activation (English)
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22 October 2012
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In this paper, the authors establish the necessary and sufficient conditions for multistationarity that take the form of linear inequality systems in terms of the stoichiometric matrix and the reaction rate-exponent matrix. They also present a sufficient condition to identify networks where the aforementioned conditions hold. To show the applicability of the theoretical results, they analyse an ODE system that is defined by the mass action network describing the extracellular signal-regulated kinase (ERK) cascade.
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mass action kinetics
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multistationarity
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linear inequalities
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