Boundary integral formulation and semi-implicit scheme coupling for modeling cells under electrical stimulation (Q527819): Difference between revisions

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Latest revision as of 18:29, 19 March 2024

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Boundary integral formulation and semi-implicit scheme coupling for modeling cells under electrical stimulation
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    Boundary integral formulation and semi-implicit scheme coupling for modeling cells under electrical stimulation (English)
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    12 May 2017
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    The authors are concerned with numerical solutions to an unsteady transmission problem for the Laplace operator with a dynamic boundary condition on a smooth interface (the temporal behavior of potential jumps across the membrane). They cast the original volume model, using the boundary multiple traces formulation for time dependent variables, into a system of integral equations. Then they solve it by a Galerkin method along with a semi-implicit second-order time-stepping and analyze the stability and convergence. Some numerical experiments for two-dimensional cells are carried out.
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    biological cell
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    electrical stimulation
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    Laplace equation
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    unsteady transmission problem
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    Hodgkin-Huxley model
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    boundary integral formulation
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    existence
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    uniqueness
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    Galerkin method
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    second-order time-stepping
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    stability
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    convergence
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    numerical experiments
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