Nonparametric equivalents of contrasts for identifying the minimum effective dose (Q1775978): Difference between revisions

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Latest revision as of 10:34, 10 June 2024

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Nonparametric equivalents of contrasts for identifying the minimum effective dose
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    Nonparametric equivalents of contrasts for identifying the minimum effective dose (English)
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    20 May 2005
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    The author considers Mann-Whitney versions of the families of contrasts (namely, pairwise, Helmert and step contrasts) and proposes two new nonparametric step-down procedures for identifying the minimum effective dose (MED) in a one-way layout with general dose-response relationship. The step-down testing scheme for determining the MED is described, critical and adjusted \(p\)-values of identified MED are obtained. Results of Monte-Carlo simulation studies directed on comparison of the relative error rate and power performance for various nonparametric step-down tests are presented and discussed.
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    dose-response study
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    Helmert contrasts
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    nonparametric test
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    pairwise contrasts
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    step contrasts
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    step-down test
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    Mann-Whitney statistics
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