Asymptotic line-of-descent distributions (Q1065744): Difference between revisions

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Latest revision as of 18:26, 14 June 2024

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Asymptotic line-of-descent distributions
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    Asymptotic line-of-descent distributions (English)
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    1984
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    In a diffusion approximation, assume that the process is extended in the past to -\(\infty\) from a time origin 0. Let \(T_{\ell}\) be the time until there are \(\ell\) lines of descent left, beginning from n at time 0. Then the quantity \(L_ n(t)\) given by \(P(L_ n(t)\leq \ell)=P(T_{\ell}\leq t)\) represents the number of lines of descent at t in the past from the time origin. Introducing a mutation parameter \(\theta >0\) in the death-process, the author observes the random variable \(T_{\ell}\) with moment generating function \[ E(e^{\phi T_{\ell}})=\prod^{n}_{j=\ell +1}(1-2\phi /j(j+\theta -1))^{-\quad 1} \] and derives asymptotic distributions for the number of non-mutant ancestors of a sample of n from a neutral infinite alleles model: Either \(L_ n(t)\) has a normal distribution or \(n-L_ n(t)\) has a Poisson distribution as \(n\to \infty\), \(t\to 0\).
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    coalescent
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    population genetics
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    diffusion approximation
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    lines of descent
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    mutation parameter
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    death-process
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    moment generating function
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    asymptotic distributions for the number of non-mutant ancestors
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    neutral infinite alleles model
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    normal distribution
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    Poisson distribution
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