Computer simulation of a cellular automata model for the immune response in a retrovirus system (Q1118541): Difference between revisions
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Latest revision as of 11:46, 30 July 2024
scientific article
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English | Computer simulation of a cellular automata model for the immune response in a retrovirus system |
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Computer simulation of a cellular automata model for the immune response in a retrovirus system (English)
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1989
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Immune response in a retrovirus system is modeled by a network of three binary cell elements to take into account some of the main functional features of T4 cells, T8 cells, and viruses. Two different intercell interactions are introduced, one of which leads to three fixed points while the other yields bistable fixed points oscillating between a healthy state and a sick state in a mean field treatment. Evolution of these cells is studied for quenched and annealed random interactions on a simple cubic lattice with a nearest neighbor interaction using inhomogeneous cellular automata. Populations of T4 cells and viral cells oscillate together with damping (with constant amplitude) for annealed (quenched) interaction on increasing the value of mixing probability B from zero to a characteristic value \(B_{ca}\) \((B_{cq})\). For higher B, the average number of T4 cells increases while that of the viral infected cells decreases monotonically on increasing B, suggesting a phase transition at \(B_{ca}(B_{cq})\).
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AIDS
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Immune response
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retrovirus system
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network of three binary cell elements
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T4 cells
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T8 cells
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viruses
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intercell interactions
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fixed points
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bistable fixed points
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healthy state
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sick state
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quenched and annealed random interactions
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cubic lattice
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nearest neighbor interaction
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inhomogeneous cellular automata
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phase transition
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