Asymptotic analyses and error estimates for a Cahn-Hilliard type phase field system modelling tumor growth (Q501552): Difference between revisions

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This paper deals with the tumor model \[ \begin{aligned} \alpha \partial_t \mu + \partial_t \varphi - \Delta \mu &= p(\varphi) (\sigma-\gamma\mu)\\ \mu &= \beta \partial_t \varphi - \Delta \varphi + F'(\varphi)\\ \partial_t \sigma -\Delta \sigma &= -p(\varphi)(\sigma-\gamma\mu) \end{aligned} \] in a bounded, smooth, spatially three-dimensional domain, where the functions \(\varphi\), \(\mu\), \(\sigma\) signify presence of tumor (\(\varphi=1\)) or healthy cells (\(\varphi=-1\)), nutrient concentration (\(\sigma\)) or a chemical potential (\(\mu\)). Here, \(\alpha\), \(\beta\), \(\gamma\) are positive constants, \(p\) is a nonnegative function and \(F\) a nonnegative double-well potential. Continuing the study of [the last author et al., Nonlinear Anal., Real World Appl. 26, 93--108 (2015; Zbl 1334.35097)], where the limit \((\alpha,\beta)\to (0,0)\) was considered, now the limits \(\beta\to 0\) for small, fixed \(\alpha\), and \(\alpha\to 0\) for fixed \(\beta\in(0,1)\) are investigated. In both cases, it is shown that the solutions converge to the (unique) solutions of the corresponding limit problems. Error estimates are given.
Property / review text: This paper deals with the tumor model \[ \begin{aligned} \alpha \partial_t \mu + \partial_t \varphi - \Delta \mu &= p(\varphi) (\sigma-\gamma\mu)\\ \mu &= \beta \partial_t \varphi - \Delta \varphi + F'(\varphi)\\ \partial_t \sigma -\Delta \sigma &= -p(\varphi)(\sigma-\gamma\mu) \end{aligned} \] in a bounded, smooth, spatially three-dimensional domain, where the functions \(\varphi\), \(\mu\), \(\sigma\) signify presence of tumor (\(\varphi=1\)) or healthy cells (\(\varphi=-1\)), nutrient concentration (\(\sigma\)) or a chemical potential (\(\mu\)). Here, \(\alpha\), \(\beta\), \(\gamma\) are positive constants, \(p\) is a nonnegative function and \(F\) a nonnegative double-well potential. Continuing the study of [the last author et al., Nonlinear Anal., Real World Appl. 26, 93--108 (2015; Zbl 1334.35097)], where the limit \((\alpha,\beta)\to (0,0)\) was considered, now the limits \(\beta\to 0\) for small, fixed \(\alpha\), and \(\alpha\to 0\) for fixed \(\beta\in(0,1)\) are investigated. In both cases, it is shown that the solutions converge to the (unique) solutions of the corresponding limit problems. Error estimates are given. / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 35Q92 / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 92C17 / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 35K57 / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 78M35 / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 35B20 / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 65N15 / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 92C50 / rank
 
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Property / Mathematics Subject Classification ID
 
Property / Mathematics Subject Classification ID: 35R35 / rank
 
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Property / zbMATH DE Number: 6672849 / rank
 
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tumor growth
Property / zbMATH Keywords: tumor growth / rank
 
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Cahn-Hilliard system
Property / zbMATH Keywords: Cahn-Hilliard system / rank
 
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reaction-diffusion equation
Property / zbMATH Keywords: reaction-diffusion equation / rank
 
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asymptotic analysis
Property / zbMATH Keywords: asymptotic analysis / rank
 
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error estimates
Property / zbMATH Keywords: error estimates / rank
 
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Asymptotic analyses and error estimates for a Cahn-Hilliard type phase field system modelling tumor growth
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    Asymptotic analyses and error estimates for a Cahn-Hilliard type phase field system modelling tumor growth (English)
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    9 January 2017
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    This paper deals with the tumor model \[ \begin{aligned} \alpha \partial_t \mu + \partial_t \varphi - \Delta \mu &= p(\varphi) (\sigma-\gamma\mu)\\ \mu &= \beta \partial_t \varphi - \Delta \varphi + F'(\varphi)\\ \partial_t \sigma -\Delta \sigma &= -p(\varphi)(\sigma-\gamma\mu) \end{aligned} \] in a bounded, smooth, spatially three-dimensional domain, where the functions \(\varphi\), \(\mu\), \(\sigma\) signify presence of tumor (\(\varphi=1\)) or healthy cells (\(\varphi=-1\)), nutrient concentration (\(\sigma\)) or a chemical potential (\(\mu\)). Here, \(\alpha\), \(\beta\), \(\gamma\) are positive constants, \(p\) is a nonnegative function and \(F\) a nonnegative double-well potential. Continuing the study of [the last author et al., Nonlinear Anal., Real World Appl. 26, 93--108 (2015; Zbl 1334.35097)], where the limit \((\alpha,\beta)\to (0,0)\) was considered, now the limits \(\beta\to 0\) for small, fixed \(\alpha\), and \(\alpha\to 0\) for fixed \(\beta\in(0,1)\) are investigated. In both cases, it is shown that the solutions converge to the (unique) solutions of the corresponding limit problems. Error estimates are given.
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    tumor growth
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    Cahn-Hilliard system
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    reaction-diffusion equation
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    asymptotic analysis
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    error estimates
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