Modeling and optimal regulation of erythropoiesis subject to Benzene intoxication (Q1774419)
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| Language | Label | Description | Also known as |
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| English | Modeling and optimal regulation of erythropoiesis subject to Benzene intoxication |
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Modeling and optimal regulation of erythropoiesis subject to Benzene intoxication (English)
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9 May 2005
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An age structured model for erythropoiesis (blood cell production and development) is given. Using the method of characteristics, the model is replaced by a delay differential equation for the total number of mature cells. Existence and uniqueness are proved for this new system. Finite element method is used to investigate it. Finally, optimal control is used to find the total number of mature cells and the number of proliferating precurser cells.
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hematopoiesis
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age structured mosel
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existence and uniqueness
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optimal control
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delay
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finite element
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