Computational analysis of CFSE proliferation assay

DOI10.1007/S00285-006-0046-6zbMath1113.92021OpenAlexW2125255512WikidataQ48923905 ScholiaQ48923905MaRDI QIDQ883800

Stephan Ehl, Dirk Roose, Tatyana Luzyanina, John T. Edwards, Sonja Mrusek, Gennadii A. Bocharov

Publication date: 12 June 2007

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-006-0046-6

zbMATH Keywords

Parameter estimationCFSE assayComputation of confidence intervalsHeterogenous compartmental modelModelling T-cell kinetics

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Physiology (general) (92C30) Cell biology (92C37)

Related Items (11)

Distributed parameter identification for a label-structured cell population dynamics model using CFSE histogram time-series data ⋮ Insights into the mechanisms of thymus involution and regeneration by modeling the glucocorticoid-induced perturbation of thymocyte populations dynamics ⋮ Positive observers for linear positive systems, and their implications ⋮ Label structured cell proliferation models ⋮ Rival approaches to mathematical modelling in immunology ⋮ Demographic modeling of transient amplifying cell population growth ⋮ Analysis and simulation of division- and label-structured population models. A new tool to analyze proliferation assays. ⋮ Estimation of cell proliferation dynamics using CFSE data ⋮ Mathematical modeling of SARS-nCoV-2 virus in Tamil Nadu, South India ⋮ Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division ⋮ Quantifying T lymphocyte turnover

Uses Software

• bootstrap

Cites Work

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• Bootstrap methods for standard errors, confidence intervals, and other measures of statistical accuracy
• Computational modelling with functional differential equations: identification, selection, and sensitivity
• Computational approaches to parameter estimation and model selection in immunology
• Estimating division and death rates from CFSE data
• Counting probability distributions: Differential geometry and model selection
• Model Selection and Multimodel Inference
• ON THE ROLE OF VARIABLE GENERATION TIME IN THE DEVELOPMENT OF A STOCHASTIC BIRTH PROCESS

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