Consequences of misspecifying assumptions in nonlinear mixed effects models.

DOI10.1016/S0167-9473(99)00076-6zbMath1054.62603MaRDI QIDQ1583064

A. Hartford, Marie Davidian

Publication date: 26 October 2000

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

zbMATH Keywords

linearizationLaplace approximationnonnormalityRandom effects

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) General nonlinear regression (62J02)

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Uses Software

• NONMEM
• SASmixed

Cites Work

• Two Taylor-series approximation methods for nonlinear mixed models
• The effect of misspecifying the random-effects distribution in linear mixed models for longitudinal data
• The Bayesian Analysis of Population Pharmacokinetic Models
• A Linear Mixed-Effects Model With Heterogeneity in the Random-Effects Population
• Estimating Equations for Parameters in Means and Covariances of Multivariate Discrete and Continuous Responses
• A note on the use of Laplace's approximation for nonlinear mixed-effects models
• On nonlinear random effects models for repeated measurements
• Nonlinear component of variance models
• The nonlinear mixed effects model with a smooth random effects density
• Laplace's approximation for nonlinear mixed models
• A New Method to Explore the Distribution of Interindividual Random Effects in Non-Linear Mixed Effects Models
• An Estimation Method for the Semiparametric Mixed Effects Model
• Population HIV‐1 Dynamics In Vivo: Applicable Models and Inferential Tools for Virological Data from AIDS Clinical Trials
• Finite Mixture Modeling with Mixture Outcomes Using the EM Algorithm
• Correcting for Measurement Error in Individual‐Level Covariates in Nonlinear Mixed Effects Models
• Approximate Inference in Generalized Linear Mixed Models
• A maximum likelihood estimation method for random coefficient regression models

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