Modeling genetic architecture: A multilinear theory of gene interaction

DOI10.1006/TPBI.2000.1508zbMath0994.92029OpenAlexW2011145067WikidataQ73598608 ScholiaQ73598608MaRDI QIDQ1597399

Thomas F. Hansen, Günter P. Wagner

Publication date: 10 October 2002

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1006/tpbi.2000.1508

zbMATH Keywords

epistasisselectionmutationsgenotype-phenotype mapcanalizationline-cross meanssegregating alleles

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

Related Items (15)

Estimating genetic architectures from artificial-selection responses: a random-effect framework ⋮ Epistasis can increase multivariate trait diversity in haploid non-recombining populations ⋮ A simple fitness proxy for structured populations with continuous traits, with case studies on the evolution of haplo-diploids and genetic dimorphisms ⋮ On the evolution of epistasis. II: A generalized Wright-Kimura framework ⋮ Multilocus population-genetic theory ⋮ On the evolution of epistasis. III: The haploid case with mutation ⋮ Effects of epistasis and the evolution of genetic architecture: exact results for a 2-locus model ⋮ Evolutionary dynamics in the two-locus two-allele model with weak selection ⋮ A computational method to detect epistatic effects contributing to a quantitative trait ⋮ Evolvability and robustness: a paradox restored ⋮ The mapping of epistatic effects onto a genealogical tree in haploid populations ⋮ The role of epistatic gene interactions in the response to selection and the evolution of evolvabil\-i\-ty ⋮ A simple model of co-evolutionary dynamics caused by epistatic selection ⋮ On the evolution of epistasis. I: Diploids under selection ⋮ Selective mating in a continuous model of epistasis

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Deleterious mutations, variable epistatic interactions, and the evolution of recombination
• Landscapes and their correlation functions
• Quantitative variability and multilocus polymorphism under epistatic selection
• Epistasis and pleiotropy as natural properties of transcriptional regulation
• Equilibria in an epistatic viability model under arbitrary strength of selection
• Evolution of gene networks by gene duplications: a mathematical model and its implications on genome organization.
• A stochastic model concerning the maintenance of genetic variability in quantitative characters.

This page was built for publication: Modeling genetic architecture: A multilinear theory of gene interaction