Evaluating the efficacies of maximum tolerated dose and metronomic chemotherapies: a mathematical approach

DOI10.1016/j.physa.2016.03.019zbMath1400.92257MaRDI QIDQ1619565

Rafael T. Guiraldello, Paulo F. A. Mancera, Marcelo L. Martins

Publication date: 13 November 2018

Published in: Physica A (Search for Journal in Brave)

Full work available at URL: http://hdl.handle.net/11449/161543

zbMATH Keywords

cancer; chemotherapy; tumor-induced angiogenesis; mathematical oncology

Mathematics Subject Classification ID

35Q92: PDEs in connection with biology, chemistry and other natural sciences

92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)

92C50: Medical applications (general)

35K51: Initial-boundary value problems for second-order parabolic systems

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Cites Work

• Unnamed Item
• On the MTD paradigm and optimal control for multi-drug cancer chemotherapy
• Multiscale modelling of tumour growth and therapy: the influence of vessel normalisation on chemotherapy
• Continuous and discrete mathematical models of tumor-induced angiogenesis
• An advanced discrete state-discrete event multiscale simulation model of the response of a solid tumor to chemotherapy: mimicking a clinical study
• Tumour eradication by antiangiogenic therapy: analysis and extensions of the model by Hahnfeldt et al. (1999)
• A mathematical model for the effect of anti-angiogenic therapy in the treatment of cancer tumours by chemotherapy
• Mathematical analysis and simulations involving chemotherapy and surgery on large human tumours under a suitable cell-kill functional response
• Modeling the Impact of Anticancer Agents on Metastatic Spreading
• Mathematical model of cancer growth controled by metronomic chemotherapies
• Optimal Control Applied to Competing Chemotherapeutic Cell-Kill Strategies
• TUMOR ANGIOGENESIS BASED ANALYTICAL MODEL FOR THE ASSESSMENT OF MCT AND MTD CHEMOTHERAPEUTIC STRATEGIES IN CANCER