Intrinsic noise and Hill dynamics in the p53 system

DOI10.1016/j.jtbi.2010.10.009zbMath1307.92081OpenAlexW1989622766WikidataQ51644296 ScholiaQ51644296MaRDI QIDQ2261628

Qi Wang, Bo Liu, Shiwei Yan

Publication date: 9 March 2015

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2010.10.009

zbMATH Keywords

noisemodelingnonlinear analysisprotein circuit

Mathematics Subject Classification ID

Applications of Markov chains and discrete-time Markov processes on general state spaces (social mobility, learning theory, industrial processes, etc.) (60J20) Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Related Items

Modeling the p53-Mdm2 dynamics triggered by DNA damage, On the role of intrinsic noise on the response of the p53-Mdm2 module, Dynamics of posttranslational modifications of p53, Codimension-3 Bifurcation in the p53 Regulatory Network Model

Cites Work

• From structure to dynamics: frequency tuning in the p53-Mdm2 network. I: Logical approach
• From structure to dynamics: frequency tuning in the p53-Mdm2 network. II: Differential and stochastic approaches
• Oscillations and bistability in the stochastic model of p53 regulation
• A unified model for studying DNA damage-induced p53--Mdm2 interaction
• Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible
• NEGATIVE FEEDBACK DYNAMICS AND OSCILLATORY ACTIVITIES IN REGULATORY BIOLOGICAL NETWORKS
• A Model for p53 Dynamics Triggered by DNA Damage