Metabolic network analysis of perfused livers under fed and fasted states: incorporating thermodynamic and futile-cycle-associated regulatory constraints

DOI10.1016/j.jtbi.2011.10.019zbMath1307.92086WikidataQ45195787 ScholiaQ45195787MaRDI QIDQ2263502

Ioannis P. Androulakis, Francois Berthiaume, Marianthi Ierapetritou, Mehmet A. Orman

Publication date: 18 March 2015

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2011.10.019

zbMATH Keywords

pathway analysis; thermodynamic constraints; futile cycles; liver metabolism; effect of fasting

Mathematics Subject Classification ID

92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)

92C40: Biochemistry, molecular biology

92C42: Systems biology, networks

Uses Software

• YANA

Cites Work

• Pathway analysis of liver metabolism under stressed condition
• Reconstructing metabolic flux vectors from extreme pathways: defining the \(\alpha\)-spectrum