Optimal control for cancer chemotherapy under tumor heterogeneity with Michealis-Menten pharmacodynamics

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Publication:2316404

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DOI10.3934/dcdsb.2019100zbMath1418.92063OpenAlexW2928986653WikidataQ128061457 ScholiaQ128061457MaRDI QIDQ2316404

Shuo Wang, Heinz Schättler

Publication date: 26 July 2019

Published in: Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/dcdsb.2019100

zbMATH Keywords

optimal control pharmacodynamics Michaelis-Menten kinetics tumor heterogeneity ensemble systems

Mathematics Subject Classification ID

Optimality conditions for problems involving partial differential equations (49K20) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

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