Heinz Schättler

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List of research outcomes

This list is not complete and representing at the moment only items from zbMATH Open and arXiv. We are working on additional sources - please check back here soon!

PublicationDate of PublicationType
On the optimal control problem for a model of the synergy of chemo‐ and immunotherapy
Optimal Control Applications & Methods
2024-04-11Paper
Bang-bang optimal controls for a mathematical model of chemo- and immunotherapy in cancer
Discrete and Continuous Dynamical Systems. Series B
2024-02-15Paper
Combination of antiangiogenic treatment with chemotherapy as a multi‐input optimal control problem
Mathematical Methods in the Applied Sciences
2023-12-19Paper
On modeling the synergy of cancer immunotherapy with radiotherapy
Communications in Nonlinear Science and Numerical Simulation
2023-02-16Paper
Pitfalls in applying optimal control to dynamical systems: an overview and editorial perspective
Discrete and Continuous Dynamical Systems. Series B
2022-09-30Paper
The structure of optimal protocols for a mathematical model of chemotherapy with antiangiogenic effects
SIAM Journal on Control and Optimization
2022-04-27Paper
On the role of pharmacometrics and the objective in optimizing cancer therapies2021-11-19Paper
Optimal control for a mathematical model for chemotherapy with pharmacometrics
Mathematical Modelling of Natural Phenomena
2021-07-19Paper
On the role of pharmacometrics in mathematical models for cancer treatments
Discrete and Continuous Dynamical Systems. Series B
2021-05-20Paper
On the role of the objective in the optimization of compartmental models for biomedical therapies
Journal of Optimization Theory and Applications
2021-05-11Paper
On the role of tumor heterogeneity for optimal cancer chemotherapy
Networks and Heterogeneous Media
2019-10-10Paper
Optimal Control for Fast, Accurate Threshold-Hitting
SIAM Journal on Control and Optimization
2019-08-30Paper
A variational approach to perturbation feedback control for optimal control problems with terminal constraints and free terminal time
Set-Valued and Variational Analysis
2019-07-26Paper
Optimal control for a mathematical model for anti-angiogenic treatment with Michaelis-Menten pharmacodynamics
Discrete and Continuous Dynamical Systems. Series B
2019-07-26Paper
Optimal control for cancer chemotherapy under tumor heterogeneity with Michealis-Menten pharmacodynamics
Discrete and Continuous Dynamical Systems. Series B
2019-07-26Paper
Optimal combined radio- and anti-angiogenic cancer therapy
Journal of Optimization Theory and Applications
2019-03-06Paper
Optimal and suboptimal protocols for a class of mathematical models of tumor anti-angiogenesis
Journal of Theoretical Biology
2018-10-15Paper
Fundamental limits of forced asynchronous spiking with integrate and fire dynamics
The Journal of Mathematical Neuroscience
2018-07-24Paper
Optimal control for a mathematical model of glioma treatment with oncolytic therapy and TNF-\(\alpha \) inhibitors
Journal of Optimization Theory and Applications
2018-04-13Paper
A computational method for the calculation of the feasibility boundary and clustering in differential-algebraic systems
IEEE Transactions on Circuits and Systems I: Regular Papers
2017-11-20Paper
Treatment of glioma with virotherapy and TNF-\(\alpha\) inhibitors: analysis as a dynamical system
Discrete and Continuous Dynamical Systems. Series B
2017-11-14Paper
Sufficient conditions for optimality for a mathematical model of drug treatment with pharmacodynamics
Opuscula Mathematica
2017-05-31Paper
On drug resistance and metronomic chemotherapy: a mathematical modeling and optimal control approach
Mathematical Biosciences and Engineering
2016-11-02Paper
Optimal control of a mathematical model for cancer chemotherapy under tumor heterogeneity
Mathematical Biosciences and Engineering
2016-10-12Paper
Tumor development under combination treatments with anti-angiogenic therapies
Lecture Notes on Mathematical Modelling in the Life Sciences
2016-09-16Paper
On optimal chemotherapy for heterogeneous tumors
Journal of Biological Systems
2016-08-12Paper
Dynamical properties of a minimally parameterized mathematical model for metronomic chemotherapy
Journal of Mathematical Biology
2016-04-05Paper
Fields of extremals and sensitivity analysis for multi-input bilinear optimal control problems
Discrete and Continuous Dynamical Systems
2016-03-09Paper
Optimal control of cancer treatments: mathematical models for the tumor microenvironment
Springer INdAM Series
2016-01-26Paper
Dynamics and control of a mathematical model for metronomic chemotherapy
Mathematical Biosciences and Engineering
2015-10-13Paper
On the dynamics of tumor-immune system interactions and combined chemo- and immunotherapy
New Challenges for Cancer Systems Biomedicine
2015-07-16Paper
Optimal control for mathematical models of cancer therapies. An application of geometric methods
Interdisciplinary Applied Mathematics
2015-07-09Paper
A 3-compartment model for chemotherapy of heterogeneous tumor populations
Acta Applicandae Mathematicae
2015-04-20Paper
On optimal singular controls for a general SIR-model with vaccination and treatment
Discrete and Continuous Dynamical Systems
2015-03-02Paper
Dynamics of tumor-immune interaction under treatment as an optimal control problem
Discrete and Continuous Dynamical Systems
2015-03-02Paper
Sufficient conditions for strong local optimality in optimal control problems with \(L_{2}\)-type objectives and control constraints
Discrete and Continuous Dynamical Systems. Series B
2014-12-04Paper
A review of optimal chemotherapy protocols: from MTD towards metronomic therapy
Mathematical Modelling of Natural Phenomena
2014-08-13Paper
Optimal controls for a mathematical model of tumor-immune interactions under targeted chemotherapy with immune boost
Discrete and Continuous Dynamical Systems. Series B
2013-11-12Paper
On the MTD paradigm and optimal control for multi-drug cancer chemotherapy
Mathematical Biosciences and Engineering
2013-07-29Paper
On optimal chemotherapy with a strongly targeted agent for a model of tumor-immune system interactions with generalized logistic growth
Mathematical Biosciences and Engineering
2013-07-29Paper
Synthesis of optimal controlled trajectories with chattering arcs2013-05-24Paper
Robustness of optimal controls for a class of mathematical models for tumor anti-angiogenesis
Mathematical Biosciences and Engineering
2013-03-19Paper
Optimal and suboptimal protocols for a mathematical model for tumor anti-angiogenesis in combination with chemotherapy
Mathematical Biosciences and Engineering
2013-03-19Paper
Perturbation feedback control: A geometric interpretation
Numerical Algebra, Control and Optimization
2012-11-13Paper
Lyapunov-Schmidt reduction for optimal control problems
Discrete and Continuous Dynamical Systems. Series B
2012-09-12Paper
On an extension of a mathematical model for tumor anti-angiogenesis
Nonlinear Analysis. Theory, Methods & Applications. Series A: Theory and Methods
2012-06-09Paper
Multi-input optimal control problems for combined tumor anti-angiogenic and radiotherapy treatments
Journal of Optimization Theory and Applications
2012-05-08Paper
Singular controls and chattering arcs in optimal control problems arising in biomedicine2012-04-18Paper
Singular controls and chattering arcs in optimal control problems arising in biomedicine2012-04-18Paper
Geometric optimal control. Theory, methods and examples
Interdisciplinary Applied Mathematics
2012-04-04Paper
Minimum-Time Frictionless Atom Cooling in Harmonic Traps
SIAM Journal on Control and Optimization
2012-03-13Paper
Optimal response to chemotherapy for a mathematical model of tumor-immune dynamics
Journal of Mathematical Biology
2012-02-24Paper
An optimal control approach to cancer treatment under immunological activity
Applicationes Mathematicae
2011-03-04Paper
Realizable protocols for optimal administration of drugs in mathematical models for anti-angiogenic treatment
Mathematical Medicine and Biology
2010-07-02Paper
On optimal delivery of combination therapy for tumors
Mathematical Biosciences
2009-12-07Paper
Scheduling of angiogenic inhibitors for Gompertzian and logistic tumor growth models
Discrete and Continuous Dynamical Systems. Series B
2009-09-16Paper
On the optimality of singular controls for a class of mathematical models for tumor anti-angiogenesis
Discrete and Continuous Dynamical Systems. Series B
2009-06-02Paper
scientific article; zbMATH DE number 5556354 (Why is no real title available?)2009-05-22Paper
A model for cancer chemotherapy with state-space constraints
Nonlinear Analysis. Theory, Methods & Applications. Series A: Theory and Methods
2009-02-04Paper
AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem
SIAM Journal on Control and Optimization
2008-06-16Paper
Optimal controls for a model with pharmacokinetics maximizing bone marrow in cancer chemo\-therapy
Mathematical Biosciences
2007-07-23Paper
Local fields of extremals for optimal control problems with state constraints of relative degree 1
Journal of Dynamical and Control Systems
2006-11-07Paper
Drug resistance in cancer chemotherapy as an optimal control problem
Discrete and Continuous Dynamical Systems. Series B
2006-06-06Paper
ANALYSIS OF A CELL-CYCLE SPECIFIC MODEL FOR CANCER CHEMOTHERAPY
Journal of Biological Systems
2006-05-10Paper
The influence of PK/PD on the structure of optimal controls in cancer chemotherapy models
Mathematical Biosciences and Engineering
2006-02-07Paper
Controlling a model for bone marrow dynamics in cancer chemotherapy
Mathematical Biosciences and Engineering
2005-05-09Paper
scientific article; zbMATH DE number 2163451 (Why is no real title available?)2005-04-29Paper
Comparison of optimal controls for a model in cancer chemotherapy withL1- andL2-type objectives
Optimization Methods & Software
2005-03-14Paper
Stratifiable families of extremals and sufficient conditions for optimality in optimal control problems
Journal of Optimization Theory and Applications
2005-01-17Paper
On the optimality of parametrized families of bang-bang trajectories.
Nonlinear Analysis. Theory, Methods & Applications. Series A: Theory and Methods
2004-08-26Paper
On generalizations of the Euler-Lagrange equation.
Nonlinear Analysis. Theory, Methods & Applications. Series A: Theory and Methods
2004-08-26Paper
A local generalized Hilbert invariant integral.
Nonlinear Analysis. Theory, Methods & Applications. Series A: Theory and Methods
2004-08-26Paper
scientific article; zbMATH DE number 2062254 (Why is no real title available?)2004-03-25Paper
Optimal controls for a 3-compartment model for cancer chemotherapy with quadratic objective
Discrete and Continuous Dynamical Systems
2004-02-23Paper
Minimization of the base transit time in semiconductor devices using optimal control
Discrete and Continuous Dynamical Systems
2004-02-23Paper
Optimal control systems governed by second-order ODEs with Dirichlet boundary data and variable parameters
Illinois Journal of Mathematics
2004-01-19Paper
Optimal bang-bang controls for a two-compartment model in cancer chemotherapy
Journal of Optimization Theory and Applications
2003-03-10Paper
Sufficient conditions for relative minima of broken extremals in optimal control theory
Journal of Mathematical Analysis and Applications
2002-07-08Paper
scientific article; zbMATH DE number 1223652 (Why is no real title available?)2001-11-19Paper
Stability of elliptic optimal control problems
Computers & Mathematics with Applications
2001-11-12Paper
A high-order generalization of the Lyusternik theorem
Nonlinear Analysis: Theory, Methods & Applications
2001-02-08Paper
scientific article; zbMATH DE number 1550760 (Why is no real title available?)2001-01-14Paper
scientific article; zbMATH DE number 1304150 (Why is no real title available?)2000-07-03Paper
scientific article; zbMATH DE number 1304145 (Why is no real title available?)2000-06-15Paper
A High-Order Generalized Local Maximum Principle
SIAM Journal on Control and Optimization
2000-03-19Paper
scientific article; zbMATH DE number 1264726 (Why is no real title available?)2000-01-10Paper
Parametrized Families of Extremals and Singularities in Solutions to the Hamilton--Jacobi--Bellman Equation
SIAM Journal on Control and Optimization
1999-11-23Paper
scientific article; zbMATH DE number 1241690 (Why is no real title available?)1999-09-21Paper
scientific article; zbMATH DE number 1193166 (Why is no real title available?)1999-06-09Paper
High-order tangent cones and their application in optimization
Nonlinear Analysis: Theory, Methods & Applications
1999-04-08Paper
High-Order Approximations and Generalized Necessary Conditions for Optimality
SIAM Journal on Control and Optimization
1999-03-31Paper
scientific article; zbMATH DE number 1223650 (Why is no real title available?)1999-03-09Paper
On singularities in solutions to the Hamilton-Jacobi-Bellman equation
Nonlinear Analysis: Theory, Methods & Applications
1998-07-16Paper
AN EXTENDED MAXIMUM PRINCIPLE
Nonlinear Analysis: Theory, Methods & Applications
1997-12-22Paper
scientific article; zbMATH DE number 1031321 (Why is no real title available?)1997-07-31Paper
scientific article; zbMATH DE number 923893 (Why is no real title available?)1997-06-03Paper
scientific article; zbMATH DE number 879942 (Why is no real title available?)1997-06-03Paper
On optimal sharing rules in discrete- and continuous-time principal-agent problems with exponential utility
Journal of Economic Dynamics and Control
1997-02-28Paper
Local bifurcations and feasibility regions in differential-algebraic systems
IEEE Transactions on Automatic Control
1996-08-26Paper
Fast time-varying phasor analysis in the balanced three-phase large electric power system
IEEE Transactions on Automatic Control
1996-07-17Paper
Second-order conditions for extremum problems with nonregular equality constraints
Journal of Optimization Theory and Applications
1996-04-01Paper
scientific article; zbMATH DE number 691529 (Why is no real title available?)1994-12-18Paper
scientific article; zbMATH DE number 691528 (Why is no real title available?)1994-12-18Paper
The first-order approach to the continuous-time principal-agent problem with exponential utility
Journal of Economic Theory
1994-06-23Paper
A synthesis of time-optimal controls in the presence of saturated singular arcs
Forum Mathematicum
1994-01-26Paper
Descent algorithms for optimal periodic output feedback control
IEEE Transactions on Automatic Control
1993-08-12Paper
Voltage dynamics: study of a generator with voltage control, transmission, and matched MW load
IEEE Transactions on Automatic Control
1993-04-01Paper
scientific article; zbMATH DE number 124712 (Why is no real title available?)1993-02-21Paper
scientific article; zbMATH DE number 19139 (Why is no real title available?)1992-06-26Paper
A local feedback synthesis of time-optimal stabilizing controls in dimension three
MCSS. Mathematics of Control, Signals, and Systems
1992-06-25Paper
scientific article; zbMATH DE number 4151228 (Why is no real title available?)1990-01-01Paper
The Structure of Small-Time Reachable Sets in Low Dimensions
SIAM Journal on Control and Optimization
1989-01-01Paper
The Local Structure of Time-Optimal Trajectories in Dimension Three under Generic Conditions
SIAM Journal on Control and Optimization
1988-01-01Paper
scientific article; zbMATH DE number 4089988 (Why is no real title available?)1988-01-01Paper
Regularity properties of time-optimal trajectories of an analytic single- input control-linear system in dimension three
Journal of Optimization Theory and Applications
1988-01-01Paper
On the Local Structure of Time-Optimal Bang-Bang Trajectories in $\mathbb{R}^3$
SIAM Journal on Control and Optimization
1988-01-01Paper
On the time-optimality of bang-bang trajectories in 𝐑³
Bulletin of the American Mathematical Society
1987-01-01Paper
On the regularity of optimal controls
ZAMP. Zeitschrift für angewandte Mathematik und Physik
1987-01-01Paper


Research outcomes over time


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