On optimal delivery of combination therapy for tumors

From MaRDI portal
Publication:1042733

DOI10.1016/j.mbs.2009.08.004zbMath1176.92033OpenAlexW2091513278WikidataQ51798408 ScholiaQ51798408MaRDI QIDQ1042733

Heinz Schättler, Helmut Maurer, Alberto d'Onofrio, Urszula Łedzewicz-Kowalewska

Publication date: 7 December 2009

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2009.08.004




Related Items

Dynamical properties of a minimally parameterized mathematical model for metronomic chemotherapyThe stability analysis of tumor-immune responses to chemotherapy system driven by Gaussian colored noisesOptimal control of vibration-based micro-energy harvestersNoise and delay enhanced stability in tumor-immune responses to chemotherapy systemDynamics and optimal control of chemotherapy for low grade gliomas: insights from a mathematical modelA deterministic and stochastic model for the system dynamics of tumor-immune responses to chemotherapyDynamical analysis of chemotherapy models with time-dependent infusionLocal controllability and optimal control for a model of combined anticancer therapy with control delaysOptimal Control of Cancer Treatments: Mathematical Models for the Tumor MicroenvironmentControl strategies for a tumor-immune system with impulsive drug delivery under a random environmentOptimal control of cancer chemotherapy with delays and state constraintsOptimal chemotherapy schedules from tumor entropySpreading speeds for a two-species competition-diffusion systemSensitivity of combined chemo- and antiangiogenic therapy results in different models describing cancer growthMathematical modeling of the immune-chemotherapeutic treatment of breast cancer under some control parametersAn optimal control problem of immuno-chemotherapy in presence of gene therapyOptimization of combined leukemia therapy by finite-dimensional optimal control modelingMathematical modelling for spatial optimization of irradiation during proton radiotherapy with nanosensitizersThe nature of Hopf bifurcation for the Gompertz model with delaysStructural stability investigation of bang-singular-bang optimal controlsMulti-input optimal control problems for combined tumor anti-angiogenic and radiotherapy treatmentsAnalysis of the Hopf bifurcation for the family of angiogenesis models. II: The case of two nonzero unequal delaysCombination of antiangiogenic treatment with chemotherapy as a multi‐input optimal control problemOptimal control for selected cancer chemotherapy ODE models: a view on the potential of optimal schedules and choice of objective functionStability analysis of the family of tumour angiogenesis models with distributed time delaysMulti-control commercial aircraft trajectory optimization in a vertical plane with state-inequality constraints via singular control theoryOn strategies on a mathematical model for leukemia therapyOptimal control problems for differential equations applied to tumor growth: state of the artStability analysis on a hybrid PDE–ODE system describing intermittent hormonal therapy of prostate cancerTumour growth control: analysis of alternative approachesOptimizing the delivery of combination therapy for tumors: A mathematical modelClosed-loop control of tumor growth by means of anti-angiogenic administrationChemotherapy of vascularised tumours: role of vessel density and the effect of vascular ``pruningDelay Differential Equations in Bio-PopulationsA survey of optimization models on cancer chemotherapy treatment planningCatalog of the optimal controls in cancer chemotherapy for the Gompertz model depending on PK/PD and the integral constraintOptimal combined radio- and anti-angiogenic cancer therapyOptimal response to chemotherapy for a mathematical model of tumor-immune dynamicsPassing to the limit 2D–1D in a model for metastatic growthAnalysis of the effectiveness of the treatment of solid tumors in two cases of drug administrationOptimal control for a mathematical model of glioma treatment with oncolytic therapy and TNF-\(\alpha \) inhibitorsOptimization of additive chemotherapy combinations for an in vitro cell cycle model with constant drug exposuresMaximization of viability time in a mathematical model of cancer therapyStochastic modelling of slow-progressing tumors: analysis and applications to the cell interplay and control of low grade gliomasA generalization of Gompertz law compatible with the Gyllenberg-Webb theory for tumour growthAnalysis of the Hopf bifurcation for the family of angiogenesis modelsOptimization of an \textit{in vitro} chemotherapy to avoid resistant tumoursOn the role of the objective in the optimization of compartmental models for biomedical therapiesOn the role of pharmacometrics in mathematical models for cancer treatmentsMaximum tolerated dose versus metronomic scheduling in the treatment of metastatic cancersCombined therapy for treating solid tumors with chemotherapy and angiogenic inhibitorsOn probabilistic certification of combined cancer therapies using strongly uncertain modelsOptimisation of Cancer Drug Treatments Using Cell Population DynamicsTumor Development Under Combination Treatments with Anti-angiogenic TherapiesTherapy strategy in tumour cells and immune system interaction mathematical modelQualitative analysis of tumor growth model under antiangiogenic therapy - choosing the effective operating point and design parameters for controller designOptimal control for a mathematical model for chemotherapy with pharmacometricsEffect of treatment on the global dynamics of delayed pathological angiogenesis modelsAnalyzing the quality robustness of chemotherapy plans with respect to model uncertaintiesOn the preliminary design of hyperthermia treatments based on infusion and heating of magnetic nanofluidsUnnamed Item



Cites Work