Optimizing the delivery of combination therapy for tumors: A mathematical model
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Publication:2977889
DOI10.1142/S1793524517500395zbMATH Open1361.92037OpenAlexW2539268134MaRDI QIDQ2977889FDOQ2977889
Authors: Clara Rojas Rodríguez, Juan Belmonte-Beitia 
Publication date: 20 April 2017
Published in: International Journal of Biomathematics (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1142/s1793524517500395
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chemotherapybang-bang controlsingular controlanti-angiogenic treatmentmathematical modeling of tumor growth
Medical applications (general) (92C50) Existence theories for optimal control problems involving ordinary differential equations (49J15) Applications of optimal control and differential games (49N90)
Cites Work
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- Chemotherapy for tumors: An analysis of the dynamics and a study of quadratic and linear optimal controls
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- Catalog of the optimal controls in cancer chemotherapy for the Gompertz model depending on PK/PD and the integral constraint
- On optimal chemotherapy for heterogeneous tumors
- Multi-input optimal control problems for combined tumor anti-angiogenic and radiotherapy treatments
- A new mathematical model for optimizing the combination between antiangiogenic and cytotoxic drugs in oncology
- The effect of finite duration inputs on the dynamics of a system: proposing a new approach for cancer treatment
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Cited In (13)
- Optimal scheduling of radiotherapy and angiogenic inhibitors
- An optimization method for treating solid tumors with combined therapy using the great deluge algorithm
- On optimal delivery of combination therapy for tumors
- Optimization of combined antitumor chemotherapy with bevacizumab by means of mathematical modeling
- The indirect bang-singular algorithm (IBSA) for singular control problems with state-inequality constraints
- Model for cancer therapy with penalty on the cost of treatment
- Multi-control commercial aircraft trajectory optimization in a vertical plane with state-inequality constraints via singular control theory
- Mathematical modeling and optimization of intratumor drug transport
- Quantitative model for efficient temporal targeting of tumor cells and neovasculature
- Mathematical modeling and optimal control problems in brain tumor targeted drug delivery strategies
- A new mathematical model for optimizing the combination between antiangiogenic and cytotoxic drugs in oncology
- Optimal control problems for differential equations applied to tumor growth: state of the art
- Mathematical modeling in scheduling cancer treatment with combination of VEGF inhibitor and chemotherapy drugs
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