Mathematical model of optimal chemotherapy strategy with allowance for cell population dynamics in a heterogeneous tumor

DOI10.1134/S0965542509110013zbMath1223.92023MaRDI QIDQ2995676

A. V. Antipov, Alexander S. Bratus'

Publication date: 4 May 2011

Published in: Computational Mathematics and Mathematical Physics (Search for Journal in Brave)

zbMATH Keywords

numerical methodsoptimal control problem

Mathematics Subject Classification ID

Applications of optimal control and differential games (49N90) Dynamical systems in biology (37N25) Medical applications (general) (92C50) Numerical methods for mathematical programming, optimization and variational techniques (65K99)

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On strategies on a mathematical model for leukemia therapy ⋮ Solution of the feedback control problem in the mathematical model of leukaemia therapy ⋮ Maximization of viability time in a mathematical model of cancer therapy ⋮ Optimization of the chemotherapy process on the base of the maximum principle ⋮ Synthesis of optimal control in a mathematical model of tumour–immune dynamics ⋮ On viable therapy strategy for a mathematical spatial cancer model describing the dynamics of malignant and healthy cells

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