Combination of antiangiogenic treatment with chemotherapy as a multi‐input optimal control problem

DOI10.1002/MMA.7977MaRDI QIDQ6180394zbMATH OpenOpenAlexFDO

Authors Urszula Ledzewicz, Heinz Schättler

Publication date 19 December 2023

Published in Mathematical Methods in the Applied Sciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/mma.7977

zbMATH Keywords

antiangiogenesiscombination therapymathematical modelingoptimal controlsingular controlsynthesis of solutions

Mathematics Subject Classification ID

Optimality conditions for problems involving ordinary differential equations (49K15) Medical applications (general) (92C50)

Cites work

• AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem
• Calculus of variations and optimal control theory. A concise introduction
• Geometric optimal control. Theory, methods and examples
• scientific article; zbMATH DE number 3505708 (Why is no real title available?)
• scientific article; zbMATH DE number 2062254 (Why is no real title available?)
• scientific article; zbMATH DE number 932672 (Why is no real title available?)
• scientific article; zbMATH DE number 3191476 (Why is no real title available?)
• Introduction to the mathematical theory of control
• Minimizing long-term tumor burden: the logic for metronomic chemotherapeutic dosing and its antiangiogenic basis
• Numerical optimisation of chemotherapy dosage under antiangiogenic treatment in the presence of drug resistance
• On optimal delivery of combination therapy for tumors
• On the role of pharmacometrics in mathematical models for cancer treatments
• On the role of tumor heterogeneity for optimal cancer chemotherapy
• Optimal bang-bang controls for a two-compartment model in cancer chemotherapy
• Optimal combined radio- and anti-angiogenic cancer therapy
• Optimal control for mathematical models of cancer therapies. An application of geometric methods
• Role of optimal control theory in cancer chemotherapy
• Singular trajectories and their role in control theory
• Singularity of controls in a simple model of acquired chemotherapy resistance
• Tumour eradication by antiangiogenic therapy: analysis and extensions of the model by Hahnfeldt et al. (1999)

Cited in

(4)

• AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem
• Optimal control of cytotoxic and antiangiogenic therapies on prostate cancer growth
• Angiogenesis inhibition and tumor-immune interactions with chemotherapy by a control set-valued method
• A local synthesis of solutions for optimizing combination therapy in cancer

This page was built for publication: Combination of antiangiogenic treatment with chemotherapy as a multi‐input optimal control problem

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6180394)