Optimal combined radio- and anti-angiogenic cancer therapy
From MaRDI portal
Publication:1730431
DOI10.1007/s10957-018-1426-yzbMath1409.49036OpenAlexW2898852451WikidataQ129024291 ScholiaQ129024291MaRDI QIDQ1730431
Heinz Schättler, Helmut Maurer, Urszula Łedzewicz-Kowalewska
Publication date: 6 March 2019
Published in: Journal of Optimization Theory and Applications (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s10957-018-1426-y
optimal controlnumerical methodsradiotherapycombination therapyanti-angiogenic treatmentsarc parameterization
Medical applications (general) (92C50) Optimality conditions for problems involving ordinary differential equations (49K15) Variational principles of physics (49S05)
Related Items
Measure Optimal Controls for Models Inspired by Biology, Optimal control for a bone metastasis with radiotherapy model using a linear objective functional, Combination of antiangiogenic treatment with chemotherapy as a multi‐input optimal control problem, On the role of the objective in the optimization of compartmental models for biomedical therapies, Optimal control for a mathematical model for chemotherapy with pharmacometrics, Optimization of antitumor radiotherapy fractionation via mathematical modeling with account of 4 R's of radiobiology
Uses Software
Cites Work
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Unnamed Item
- A Modeling Language for Mathematical Programming
- Optimal scheduling of radiotherapy and angiogenic inhibitors
- Geometric optimal control. Theory, methods and examples
- Structural stability investigation of bang-singular-bang optimal controls
- Multi-input optimal control problems for combined tumor anti-angiogenic and radiotherapy treatments
- Bang-singular-bang extremals: sufficient optimality conditions
- Introduction to sensitivity and stability analysis in nonlinear programming
- Switching time optimization for bang-bang and singular controls
- On optimal delivery of combination therapy for tumors
- SQP-methods for solving optimal control problems with control and state constraints: Adjoint variables, sensitivity analysis and real-time control
- Quadratic order conditions for bang-singular extremals
- Singular trajectories and their role in control theory
- Optimal and suboptimal protocols for a mathematical model for tumor anti-angiogenesis in combination with chemotherapy
- Optimal control for mathematical models of cancer therapies. An application of geometric methods
- On the implementation of an interior-point filter line-search algorithm for large-scale nonlinear programming
- AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem