Multi-input optimal control problems for combined tumor anti-angiogenic and radiotherapy treatments
DOI10.1007/S10957-011-9954-8zbMATH Open1237.49046OpenAlexW2006847833MaRDI QIDQ415424FDOQ415424
Authors: Heinz Schättler, Urszula Ledzewicz
Publication date: 8 May 2012
Published in: Journal of Optimization Theory and Applications (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s10957-011-9954-8
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Medical applications (general) (92C50) Control problems involving ordinary differential equations (34H05) Optimality conditions for problems involving ordinary differential equations (49K15) Linear-quadratic optimal control problems (49N10)
Cites Work
- Singular trajectories and their role in control theory
- Optimal scheduling of radiotherapy and angiogenic inhibitors
- Lipschitz Stability of Broken Extremals in Bang-Bang Control Problems
- On Stability of Bang-Bang Type Controls
- Regular Synthesis and Sufficiency Conditions for Optimality
- Introduction to the mathematical theory of control
- Second-order optimality conditions for bang-bang control problems
- ANALYSIS OF A CELL-CYCLE SPECIFIC MODEL FOR CANCER CHEMOTHERAPY
- Title not available (Why is that?)
- On optimal delivery of combination therapy for tumors
- Tumour eradication by antiangiogenic therapy: analysis and extensions of the model by Hahnfeldt et al. (1999)
- Robustness of optimal controls for a class of mathematical models for tumor anti-angiogenesis
- A general framework for modeling tumor-immune system competition and immunotherapy: Mathematical analysis and biomedical inferences
- A Mathematical Tumor Model with Immune Resistance and Drug Therapy: An Optimal Control Approach
- AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem
- A family of models of angiogenesis and anti-angiogenesis anti-cancer therapy
- Optimal Control Applied to Cell-Cycle-Specific Cancer Chemotherapy
- Role of optimal control theory in cancer chemotherapy
- Optimal controls for a model with pharmacokinetics maximizing bone marrow in cancer chemo\-therapy
- Scheduling of angiogenic inhibitors for Gompertzian and logistic tumor growth models
- New approach to modeling of antiangiogenic treatment on the basis of Hahnfeldt et al. model
- Title not available (Why is that?)
- Optimal bang-bang controls for a two-compartment model in cancer chemotherapy
- On Singular Extremals in the Time Minimal Control Problem in $\mathbb{R}^3 $
- The response to antiangiogenic anticancer drugs that inhibit endothelial cell proliferation
Cited In (44)
- Pointwise second-order necessary optimality conditions and second-order sensitivity relations in optimal control
- Pontryagin-type conditions for optimal muscular force response to functional electrical stimulations
- Tangency property and prior-saturation points in minimal time problems in the plane
- Qualitative analysis of tumor growth model under antiangiogenic therapy -- choosing the effective operating point and design parameters for controller design
- Optimal combined radio- and anti-angiogenic cancer therapy
- Finite-horizon parameterizing manifolds, and applications to suboptimal control of nonlinear parabolic PDEs
- Approximation of optimal control surfaces for \(2\times 2\) skew-symmetric evolutionary game dynamics
- Mathematical modeling of oxygen control in biocell composting plants
- Optimal medication for tumors modeled by a Cahn-Hilliard-Brinkman equation
- Loss control regions in optimal control problems
- Optimal controls of the highly active antiretroviral therapy
- On the role of the objective in the optimization of compartmental models for biomedical therapies
- Volatile opinions and optimal control of vaccine awareness campaigns: chaotic behaviour of the forward-backward sweep algorithm vs. heuristic direct optimization
- Second order necessary conditions for endpoints-constrained optimal control problems on Riemannian manifolds
- Constrained charge-balanced minimum-power controls for spiking neuron oscillators
- Optimizing the delivery of combination therapy for tumors: A mathematical model
- Second-order optimality conditions for singular extremals in optimal control problems with equality endpoint constraints
- Optimal control for a mathematical model for chemotherapy with pharmacometrics
- A stochastic dynamic multiobjective model for sustainable decision making
- Time-optimal control of concentration changes in the chemostat with one single species
- An optimal control approach for the treatment of solid tumors with angiogenesis inhibitors
- Optimal control: theory and application to science, engineering, and social sciences
- A geometrically based criterion to avoid infimum gaps in optimal control
- Optimal spiral-like solutions near a singular extremal in a two-input control problem
- Modeling of mouse experiments suggests that optimal anti-hormonal treatment for breast cancer is diet-dependent
- Optimal control for a mathematical model of glioma treatment with oncolytic therapy and TNF-\(\alpha \) inhibitors
- Optimal weekly scheduling in fractionated radiotherapy: effect of an upper bound on the dose fraction size
- Time-optimal velocity tracking control for differential drive robots
- Optimal control theory and advanced optimality conditions for a diffuse interface model of tumor growth
- Tumor development under combination treatments with anti-angiogenic therapies
- AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem
- On modeling the synergy of cancer immunotherapy with radiotherapy
- Neighborhood of the second-order singular regime in problems with control in a disk
- Optimal control of a SIR epidemic with ICU constraints and target objectives
- Optimal and suboptimal protocols for a mathematical model for tumor anti-angiogenesis in combination with chemotherapy
- Pointwise second-order necessary conditions for optimal control problems evolved on Riemannian manifolds
- Pareto optimization of resonances and minimum-time control
- High-order tangent cones and their application in optimization
- Asymptotic analysis and optimal control of an integro-differential system modelling healthy and cancer cells exposed to chemotherapy
- Linear-quadratic optimal sampled-data control problems: convergence result and Riccati theory
- Time-optimal control of linear time invariant systems between two arbitrary states
- On the role of pharmacometrics and the objective in optimizing cancer therapies
- Optimal control problems for differential equations applied to tumor growth: state of the art
- Maximization of viability time in a mathematical model of cancer therapy
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