A general framework for modeling tumor-immune system competition and immunotherapy: Mathematical analysis and biomedical inferences

From MaRDI portal
Publication:2565761

DOI10.1016/j.physd.2005.06.032zbMath1087.34028arXiv1309.3337OpenAlexW2107760337WikidataQ57259092 ScholiaQ57259092MaRDI QIDQ2565761

Alberto d'Onofrio

Publication date: 28 September 2005

Published in: Physica D (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1309.3337




Related Items

Reproducing kernel Hilbert space method for the numerical solutions of fractional cancer tumor modelsSampled-data output tracking control based on T-S fuzzy model for cancer-tumor-immune systemsChaotic transitions in a tumor-Immune model under chemotherapy treatmentDynamical properties of a minimally parameterized mathematical model for metronomic chemotherapyA study of behaviour for immune and tumor cells in immunogenetic tumour model with non-singular fractional derivativeAnalysis of non-autonomous stochastic Gompertz model with delayIdentifying and characterising the impact of excitability in a mathematical model of tumour-immune interactionsThe impact of distributed time delay in a tumor-immune interaction systemMixed immunotherapy and chemotherapy of tumors: feedback design and model updating schemesAnalysis of the dynamics of a tumor-immune system with chemotherapy and immunotherapy and quadratic optimal controlStochastic dynamics of Michaelis-Menten kinetics based tumor-immune interactionsHYBRID TWO SCALES MATHEMATICAL TOOLS FOR ACTIVE PARTICLES MODELLING COMPLEX SYSTEMS WITH LEARNING HIDING DYNAMICSAvoiding healthy cells extinction in a cancer modelDynamic aspects of tumour–immune system interaction under a periodic immunotherapyCHAOS IN A THREE-DIMENSIONAL CANCER MODELOptimal Control of Cancer Treatments: Mathematical Models for the Tumor MicroenvironmentCo-dimension two bifurcations analysis of a delayed tumor model with Allee effectMathematical modeling approach of cancer immunoediting reveals new insights in targeted-therapy and timing plan of cancer treatmentThe tumor growth paradox and immune system-mediated selection for cancer stem cellsModeling cancer immunotherapy: assessing the effects of lymphocytes on cancer cell growth and motilityModeling the dichotomy of the immune response to cancer: cytotoxic effects and tumor-promoting inflammationDiffusion modeling of tumor-CD\(4^+\)-cytokine interactions with treatments: asymptotic behavior and stationary patternsDynamical Analysis of a Melanoma Model with Immune ResponseMetamodeling the learning-hiding competition between tumours and the immune system: A kinematic approachComplicated dynamics of tumor-immune system interaction model with distributed time delayStability and controllability issues in mathematical modeling of the intensive treatment of leukemiaOptimization of combined leukemia therapy by finite-dimensional optimal control modelingAncestral inference in tumors: how much can we know?A nonlinear mathematical model of cell-mediated immune response for tumor phenotypic heterogeneityThe nature of Hopf bifurcation for the Gompertz model with delaysOn modeling the synergy of cancer immunotherapy with radiotherapyMulti-input optimal control problems for combined tumor anti-angiogenic and radiotherapy treatmentsAn immune system-tumour interactions model with discrete time delay: model analysis and validationInteractions between the immune system and cancer: A brief review of non-spatial mathematical modelsInfluence of distributed delays on the dynamics of a generalized immune system cancerous cells interactions modelMathematical modelling of the inhibitory role of regulatory T cells in tumor immune responseMathematical modeling on helper T cells in a tumor immune systemEffect of stem cell turnover rates on protection against cancer and agingMethods for determining key components in a mathematical model for tumor-immune dynamics in multiple myelomaCOMPLEXITY OF A DELAYED PREDATOR–PREY MODEL WITH IMPULSIVE HARVEST AND HOLLING TYPE II FUNCTIONAL RESPONSEModelling effects of a chemotherapeutic dose response on a stochastic tumour-immune modelChemotherapy of vascularised tumours: role of vessel density and the effect of vascular ``pruningTumour suppression by immune system through stochastic oscillationsBounding the dynamics of a chaotic-cancer mathematical modelResponse of immunotherapy to tumour-TICLs interactions: a travelling wave analysisBifurcations of tumor-immune competition systems with delayStability of a Mathematical Model with Piecewise Constant Arguments for Tumor-Immune Interaction Under Drug TherapyDynamical behaviour of a tumor-immune system with chemotherapy and optimal controlA dynamical model of tumour immunotherapyModeling the effect of immunotherapies on human castration-resistant prostate cancerChemotherapy for tumors: An analysis of the dynamics and a study of quadratic and linear optimal controlsOptimal response to chemotherapy for a mathematical model of tumor-immune dynamicsA simple model of pathogen-immune dynamics including specific and non-specific immunityPermanence and global attractivity of stage-structured predator-prey model with continuous harvesting on predator and impulsive stocking on preyA structural methodology for modeling immune-tumor interactions including pro- and anti-tumor factors for clinical applicationsDual role of delay effects in a tumour–immune systemOptimal control for a mathematical model of glioma treatment with oncolytic therapy and TNF-\(\alpha \) inhibitorsStability and bifurcation analysis of a mathematical model for tumor-immune interaction with piecewise constant arguments of delayQualitative analysis of second-order models of tumor-immune system competitionCost-effectiveness analysis of optimal strategy for tumor treatmentAnalysis of a stochastic tumor-immune model with regime switching and impulsive perturbationsPeriodic boundary value problems for first order functional differential equations with impulseChaos control in three dimensional cancer model by state space exact linearization based on Lie algebraMonotone method for a system of nonlinear mixed type implicit impulsive integro-differential equations in Banach spacesMetamodeling tumor-immune system interaction, tumor evasion and immunotherapyDeveloping and studying the dynamical behavior of a nonlinear mathematical model for cancers with tumor by considering immune system roleStage-structured impulsive \(SI\) model for pest managementOptimal chemotherapy in cancer treatment: state dependent Riccati equation control and extended Kalman filterA mathematical model of the enhancement of tumor vaccine efficacy by immunotherapyOn Some Dynamical Properties of a Seven-Dimensional Cancer Model with ImmunotherapyTumor evasion from immune control: Strategies of a MISS to become a MASSThreshold for extinction and survival in stochastic tumor immune systemA generalization of Gompertz law compatible with the Gyllenberg-Webb theory for tumour growthSurvival analysis for tumor cells in stochastic switching environmentStability analysis of nonlinear time-delayed systems with application to biological modelsExploring the role of host-tumor interactions in tumor growth and regressionExcitation-Induced Stability and Phase Transition: A ReviewDelay-induced oscillatory dynamics of tumour-immune system interactionNonlinear dynamics in tumor-immune system interaction models with delaysSpatiotemporal effects of a possible chemorepulsion of tumor cells by immune system effectorsOptimization of combination therapy for chronic myeloid leukemia with dosing constraintsPeriodic solutions of a tumor-immune system interaction under a periodic immunotherapyResonance of the epidemic threshold in a periodic environmentA minimal modeling framework of radiation and immune system synergy to assist radiotherapy planningSpecies diversity and predation strategies in a multiple species predator-prey modelA size and space structured model describing interactions of tumor cells with immune cells reveals cancer persistent equilibrium states in tumorigenesisMathematical modeling and dynamic analysis of anti-tumor immune responseTumor Development Under Combination Treatments with Anti-angiogenic TherapiesBifurcation Analysis in a Cancer Growth ModelCancer-induced immunosuppression can enable effectiveness of immunotherapy through bistability generation: a mathematical and computational examinationОпухолевый рост и возможности математического моделирования системных процессовSeparable transition density in the hybrid model for tumor-immune system competitionTUMOR-IMMUNE SYSTEM INTERACTION: MODELING THE TUMOR-STIMULATED PROLIFERATION OF EFFECTORS AND IMMUNOTHERAPYGlobal stability and optimisation of a general impulsive biological control modelDynamical analysis of tumor-immune-help T cells systemDynamical Behaviors of the Tumor-Immune System in a Stochastic EnvironmentOn optimal delivery of combination therapy for tumorsComplex dynamic behaviors of a tumor-immune system with two delays in tumor actionsFURTHER RESULTS ON POSITIVE PERIODIC SOLUTIONS OF IMPULSIVE FUNCTIONAL DIFFERENTIAL EQUATIONS AND APPLICATIONSResponse of patients with melanoma to immune checkpoint blockade -- insights gleaned from analysis of a new mathematical mechanistic modelA NEW MATHEMATICAL MODELING AND SUB-OPTIMAL CHEMOTHERAPY OF CANCERMost probable trajectories in a two-dimensional tumor-immune system under stochastic perturbationAnalysis of a cancer dormancy model and control of immuno-therapy



Cites Work


This page was built for publication: A general framework for modeling tumor-immune system competition and immunotherapy: Mathematical analysis and biomedical inferences