Optimal control for a mathematical model of glioma treatment with oncolytic therapy and TNF- inhibitors

DOI10.1007/S10957-018-1218-4zbMATH Open1390.49019OpenAlexW2788404984MaRDI QIDQ1743540FDOQ1743540

Authors: Elzbieta Ratajczyk, Heinz Schättler, Urszula Ledzewicz 

Publication date: 13 April 2018

Published in: Journal of Optimization Theory and Applications (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10957-018-1218-4

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zbMATH Keywords

optimal controlsingular controlhigh order necessary conditions for optimalityoncolytic therapy

Mathematics Subject Classification ID

Optimality conditions for problems involving ordinary differential equations (49K15) Control/observation systems governed by ordinary differential equations (93C15)

Cites Work

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Cited In (13)

• Analysis of a delayed and diffusive oncolytic M1 virotherapy model with immune response
• Global dynamics of reaction-diffusion oncolytic M1 virotherapy with immune response
• On the dynamics and optimal control of a mathematical model of neuroblastoma and its treatment: insights from a mathematical model
• Slow-fast model and therapy optimization for oncolytic treatment of tumors
• Optimal control of mathematical models for the radiotherapy of gliomas: the scalar case
• A mathematical model for oncolytic virus spread using the telegraph equation
• The role of TNF-\(\alpha\) inhibitor in glioma virotherapy: a mathematical model
• A strategy of optimal efficacy of T11 target structure in the treatment of brain tumor
• Treatment of glioma with virotherapy and TNF-\(\alpha\) inhibitors: analysis as a dynamical system
• Mathematical modeling and optimal control problems in brain tumor targeted drug delivery strategies
• Optimal control for a bone metastasis with radiotherapy model using a linear objective functional
• Optimal control of combination immunotherapy for a virtual murine cohort in a glioblastoma-immune dynamics model
• Application of control theory in a delayed-infection and immune-evading oncolytic virotherapy

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