Optimal control for mathematical models of cancer therapies. An application of geometric methods

From MaRDI portal
Publication:2353898

DOI10.1007/978-1-4939-2972-6zbMath1331.92008OpenAlexW4245893543MaRDI QIDQ2353898

Heinz Schättler, Urszula Łedzewicz-Kowalewska

Publication date: 9 July 2015

Published in: Interdisciplinary Applied Mathematics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/978-1-4939-2972-6




Related Items (77)

Measure Optimal Controls for Models Inspired by BiologyOptimizing the quarantine cost for suppression of the COVID-19 epidemic in MexicoOptimization of economic indicators with delayed asset commissioningMathematical modeling and control of the cell dynamics in leprosyRobust optimal control of compartmental models in epidemiology: application to the COVID-19 pandemicOptimal control of a mathematical model for cancer chemotherapy under tumor heterogeneityOn drug resistance and metronomic chemotherapy: a mathematical modeling and optimal control approachThe role of TNF-\(\alpha\) inhibitor in glioma virotherapy: a mathematical modelAsymptotic analysis and optimal control of an integro-differential system modelling healthy and cancer cells exposed to chemotherapyOptimal control problem for a general reaction-diffusion tumor-immune interaction system of mixed immunotherapy and chemotherapyThe Structure of Optimal Protocols for a Mathematical Model of Chemotherapy with Antiangiogenic EffectsDendritic immunotherapy improvement for an optimal control murine modelMathematical model of optimal chemotherapy and oncolytic virotherapyControl of tumor growth distributions through kinetic methodsSensitivity of combined chemo- and antiangiogenic therapy results in different models describing cancer growthOptimal control applied to a generalized Michaelis-Menten model of CML therapyUnnamed ItemChemotherapy and immunotherapy for tumors: a study of quadratic optimal controlOptimal control for a bone metastasis with radiotherapy model using a linear objective functionalPhenotype control techniques for Boolean gene regulatory networksTowards optimal control of amyloid fibrillationCombination of direct methods and homotopy in numerical optimal control: application to the optimization of chemotherapy in cancerOptimizing combination therapy in a murine model of HER2+ breast cancerOptimal control problems for a mathematical model of the treatment of psoriasisOptimal Control of the Controlled Lotka–Volterra Equations with Applications. The Permanent CaseOn the optimal control problem for a model of the synergy of chemo‐ and immunotherapyOn modeling the synergy of cancer immunotherapy with radiotherapyBang-bang optimal controls for a mathematical model of chemo- and immunotherapy in cancerAn optimization method for treating solid tumors with combined therapy using the great deluge algorithmModeling the dynamics of heterogeneity of solid tumors in response to chemotherapyLearning-based sensitivity analysis and feedback design for drug delivery of mixed therapy of cancer in the presence of high model uncertaintiesCombination of antiangiogenic treatment with chemotherapy as a multi‐input optimal control problemOptimal control problems for differential equations applied to tumor growth: state of the artOptimal Control for Anticancer TherapyModeling of mouse experiments suggests that optimal anti-hormonal treatment for breast cancer is diet-dependentCompetition between populations: preventing domination of resistant population using optimal controlPhysiologically Structured Cell Population Dynamic Models with Applications to Combined Drug Delivery Optimisation in OncologyOn a multiobjective optimal control of a tumor growth model with immune response and drug therapiesStability analysis of a class of non-simultaneous interconnected impulsive systemsOptimal control theory and advanced optimality conditions for a diffuse interface model of tumor growthA MODEL OF THE OPTIMAL IMMUNOTHERAPY OF PSORIASIS BY INTRODUCING IL-10 AND IL-22 INHIBITORSInfinite horizon cancer treatment model with isoperimetrical constraint: existence of optimal solutions and numerical analysisOptimal control problem for a general reaction-diffusion tumor-immune system with chemotherapyOptimal combined radio- and anti-angiogenic cancer therapyOptimal control of bacterial growth for the maximization of metabolite productionOptimal Control Problem of a Metronomic ChemotherapyOptimal Strategies of the Psoriasis Treatment by Suppressing the Interaction Between T-Lymphocytes and Dendritic CellsGlobal solvability and optimal control to a haptotaxis cancer invasion model with two cancer cell speciesIdentification of some unknown parameters in an aggressive-invasive cancer model using adjoint approachOptimal control for a mathematical model of glioma treatment with oncolytic therapy and TNF-\(\alpha \) inhibitorsOptimization of additive chemotherapy combinations for an in vitro cell cycle model with constant drug exposuresMaximization of viability time in a mathematical model of cancer therapyOptimal medication for tumors modeled by a Cahn-Hilliard-Brinkman equationSufficient conditions for optimality for a mathematical model of drug treatment with pharmacodynamicsOn the role of the objective in the optimization of compartmental models for biomedical therapiesOn the role of pharmacometrics in mathematical models for cancer treatmentsMicroscopic description of DNA thermal denaturationA new fractional model and optimal control of a tumor-immune surveillance with non-singular derivative operatorOptimization of combination therapy for chronic myeloid leukemia with dosing constraintsOptiDose: computing the individualized optimal drug dosing regimen using optimal controlCombined therapy for treating solid tumors with chemotherapy and angiogenic inhibitorsOptimal strategies in the treatment of cancers in the Lotka-Volterra mathematical model of competitionDynamics of tumor growth: chemotherapy and integrative oncologyOptimal control and positional controllability in a one-sector economyOptimal controls of the highly active antiretroviral therapyOn a third-order singular arc of optimal control in a minimization problem for a mathematical model of psoriasis treatmentEvolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured modelOpen quasispecies models: stability, optimization, and distributed extensionPitfalls in applying optimal control to dynamical systems: an overview and editorial perspectiveOn the role of tumor heterogeneity for optimal cancer chemotherapyNumerical optimal control of a size-structured PDE model for metastatic cancer treatmentMultiobjective approach in the treatment of cancerOptimal control for a mathematical model for chemotherapy with pharmacometricsOptimal control and pattern formation for a haptotaxis model of solid tumor invasionLotka-Volterra competition model with a nonmonotone therapy function for finding optimal strategies in the treatment of blood cancersOptimal Control of Vaccination and Plasma Transfusion with Potential Usefulness for Covid-19Optimization of antitumor radiotherapy fractionation via mathematical modeling with account of 4 R's of radiobiology




This page was built for publication: Optimal control for mathematical models of cancer therapies. An application of geometric methods