Optimal medication for tumors modeled by a Cahn-Hilliard-Brinkman equation

DOI10.1007/s00526-019-1579-zzbMath1418.35246arXiv1811.07783OpenAlexW2963464761WikidataQ115387161 ScholiaQ115387161MaRDI QIDQ2002008

Patrik Knopf, Matthias Ebenbeck

Publication date: 11 July 2019

Published in: Calculus of Variations and Partial Differential Equations (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1811.07783

Mathematics Subject Classification ID

Optimality conditions for problems involving partial differential equations (49K20) Medical applications (general) (92C50) Stokes and related (Oseen, etc.) flows (76D07) Existence theories for optimal control problems involving partial differential equations (49J20) Nonlinear initial, boundary and initial-boundary value problems for nonlinear parabolic equations (35K61)

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Cites Work

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• On a Cahn-Hilliard type phase field system related to tumor growth
• Multi-input optimal control problems for combined tumor anti-angiogenic and radiotherapy treatments
• Analysis of a Cahn-Hilliard system with non-zero Dirichlet conditions modeling tumor growth with chemotaxis
• Optimal control for the convective Cahn-Hilliard equation in 2D case
• Parameter identification via optimal control for a Cahn-Hilliard-chemotaxis system with a variable mobility
• Optimization of cytostatic leukemia therapy in an advection-reaction-diffusion model
• Role of optimal control theory in cancer chemotherapy
• On Stokes operators with variable viscosity in bounded and unbounded domains
• Compact sets in the space \(L^ p(0,T;B)\)
• Asymptotic limits and optimal control for the Cahn-Hilliard system with convection and dynamic boundary conditions
• Optimal control of treatment time in a diffuse interface model of tumor growth
• On a Cahn-Hilliard-Darcy system for tumour growth with solution dependent source terms
• Analysis of a Cahn-Hilliard-Brinkman model for tumour growth with chemotaxis
• Optimal distributed control of a Cahn-Hilliard-Darcy system with mass sources
• Long-time dynamics and optimal control of a diffuse interface model for tumor growth
• Optimal distributed control of an extended model of tumor growth with logarithmic potential
• Global weak solutions and asymptotic limits of a Cahn-Hilliard-Darcy system modelling tumour growth
• Multiphase modelling of tumour growth and extracellular matrix interaction: mathematical tools and applications
• Nonlinear simulations of solid tumor growth using a mixture model: invasion and branching
• Well-posedness and long-time behavior of a non-autonomous Cahn-Hilliard-Darcy system with mass source modeling tumor growth
• Optimal control for mathematical models of cancer therapies. An application of geometric methods
• A Cahn–Hilliard–Darcy model for tumour growth with chemotaxis and active transport
• Optimal control of the convective Cahn–Hilliard equation
• Distributed Optimal Control of the Cahn–Hilliard System Including the Case of a Double-Obstacle Homogeneous Free Energy Density
• Numerical simulation of a thermodynamically consistent four-species tumor growth model
• Optimal Boundary Control of a Viscous Cahn--Hilliard System with Dynamic Boundary Condition and Double Obstacle Potentials
• An Introduction to the Mathematical Theory of the Navier-Stokes Equations
• GENERAL DIFFUSE-INTERFACE THEORIES AND AN APPROACH TO PREDICTIVE TUMOR GROWTH MODELING
• On a diffuse interface model of tumour growth
• Well-posedness of a Cahn–Hilliard system modelling tumour growth with chemotaxis and active transport
• A multiphase Cahn–Hilliard–Darcy model for tumour growth with necrosis
• Optimal Velocity Control of a Viscous Cahn--Hilliard System with Convection and Dynamic Boundary Conditions
• Vanishing parameter for an optimal control problem modeling tumor growth
• On a Cahn--Hilliard--Brinkman Model for Tumor Growth and Its Singular Limits
• Formal asymptotic limit of a diffuse-interface tumor-growth model
• Optimal distributed control of a diffuse interface model of tumor growth