Application of control theory in a delayed-infection and immune-evading oncolytic virotherapy

DOI10.3934/mbe.2020126zbMath1470.92146OpenAlexW3006662660WikidataQ90792031 ScholiaQ90792031MaRDI QIDQ2050026

Taeyong Lee, Jeehyun Lee, Adrianne L. Jenner, Peter S. Kim

Publication date: 27 August 2021

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2020126

zbMATH Keywords

optimal controlpartial differential equationscancervirusoncolytic virotherapy

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Medical applications (general) (92C50) Existence theories for optimal control problems involving partial differential equations (49J20)

Related Items (1)

Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: a mathematical approach

Cites Work

• Optimal control for a mathematical model of glioma treatment with oncolytic therapy and TNF-\(\alpha \) inhibitors
• A mathematical model of oncolytic virotherapy with time delay
• Model-driven approaches for in vitro combination therapy using ONYX-015 replicating oncolytic adenovirus
• Oncolytic virotherapy for tumours following a Gompertz growth law
• A Mathematical Tumor Model with Immune Resistance and Drug Therapy: An Optimal Control Approach
• An Interior Point Algorithm for Large-Scale Nonlinear Programming

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