Behavior of tumors under nonstationary therapy

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Publication:1867933

DOI10.1016/S0167-2789(03)00005-8zbMATH Open1011.92028arXivmath-ph/0203057OpenAlexW2128191474MaRDI QIDQ1867933FDOQ1867933


Authors: L. Morales Molina, J. C. Antoranz, Marcelo Chacón Reyes, O. Sotolongo-Costa, Daniel Rodríguez-Pérez Edit this on Wikidata


Publication date: 2 April 2003

Published in: Physica D (Search for Journal in Brave)

Abstract: We present a model for the interaction dynamics of lymphocytes-tumor cells population. This model reproduces all known states for the tumor. Futherly,we develop it taking into account periodical immunotheraphy treatment with cytokines alone. A detailed analysis for the evolution of tumor cells as a function of frecuency and theraphy burden applied for the periodical treatment is carried out. Certain threshold values for the frecuency and applied doses are derived from this analysis. So it seems possible to control and reduce the growth of the tumor. Also, constant values for cytokines doses seems to be a succesful treatment.


Full work available at URL: https://arxiv.org/abs/math-ph/0203057




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