Behavior of tumors under nonstationary therapy
From MaRDI portal
Publication:1867933
DOI10.1016/S0167-2789(03)00005-8zbMATH Open1011.92028arXivmath-ph/0203057OpenAlexW2128191474MaRDI QIDQ1867933FDOQ1867933
Authors: L. Morales Molina, J. C. Antoranz, Marcelo Chacón Reyes, O. Sotolongo-Costa, Daniel Rodríguez-Pérez
Publication date: 2 April 2003
Published in: Physica D (Search for Journal in Brave)
Abstract: We present a model for the interaction dynamics of lymphocytes-tumor cells population. This model reproduces all known states for the tumor. Futherly,we develop it taking into account periodical immunotheraphy treatment with cytokines alone. A detailed analysis for the evolution of tumor cells as a function of frecuency and theraphy burden applied for the periodical treatment is carried out. Certain threshold values for the frecuency and applied doses are derived from this analysis. So it seems possible to control and reduce the growth of the tumor. Also, constant values for cytokines doses seems to be a succesful treatment.
Full work available at URL: https://arxiv.org/abs/math-ph/0203057
Recommendations
- Periodically pulsed immunotherapy in a mathematical model of tumor, CD4\(^+\) T cells, and antitumor cytokine interactions
- Dynamic aspects of tumour–immune system interaction under a periodic immunotherapy
- A general framework for modeling tumor-immune system competition and immunotherapy: Mathematical analysis and biomedical inferences
- scientific article; zbMATH DE number 426420
- Qualitative behavior of systems of tumor-\(\mathrm{CD}4^{+}\)-cytokine interactions with treatments
Cites Work
- Nonlinear oscillations, dynamical systems, and bifurcations of vector fields
- Title not available (Why is that?)
- Modeling immunotherapy of the tumor -- immune interaction
- Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis
- Modeling tumor regrowth and immunotherapy
- Immune surveillance and neoplasia. I: A minimal mathematical model
- A survey of models for tumor-immune system dynamics
- Bistability in fluctuating environments. Implications in tumor immunology
- Title not available (Why is that?)
- Title not available (Why is that?)
- Title not available (Why is that?)
- Title not available (Why is that?)
Cited In (35)
- Influence of distributed delays on the dynamics of a generalized immune system cancerous cells interactions model
- Biphasic behaviour in malignant invasion
- Fractional development under periodic forcing
- Identifying and characterising the impact of excitability in a mathematical model of tumour-immune interactions
- Phenomenological model of tumors
- Stability analysis and numerical simulations via fractional calculus for tumor dormancy models
- Excitation-induced stability and phase transition: A review
- Title not available (Why is that?)
- An immune system-tumour interactions model with discrete time delay: model analysis and validation
- Mathematical modelling of the inhibitory role of regulatory T cells in tumor immune response
- A dynamical model of tumour immunotherapy
- The Assessment of Tumour Response to Treatment
- Periodic solutions of a tumor-immune system interaction under a periodic immunotherapy
- Modelling lymphoma therapy and outcome
- $\mathcal{P}\mathcal{T}$ -symmetric model of immune response
- Study of dose-dependent combination immunotherapy using engineered T cells and IL-2 in cervical cancer
- Interactions between the immune system and cancer: A brief review of non-spatial mathematical models
- Mixed immunotherapy and chemotherapy of tumors: modeling, applications and biological interpretations
- Dynamic aspects of tumour–immune system interaction under a periodic immunotherapy
- Nonlinear dynamics in tumor-immune system interaction models with delays
- Qualitative analysis of second-order models of tumor-immune system competition
- A general framework for modeling tumor-immune system competition and immunotherapy: Mathematical analysis and biomedical inferences
- Mathematical modeling approach of cancer immunoediting reveals new insights in targeted-therapy and timing plan of cancer treatment
- Tumour-host dynamics under radiotherapy
- Stochastic resonance in a tumor-immune system subject to bounded noises and time delay
- Reproducing kernel Hilbert space method for the numerical solutions of fractional cancer tumor models
- Stability of a Mathematical Model with Piecewise Constant Arguments for Tumor-Immune Interaction Under Drug Therapy
- Modeling cancer immunotherapy: assessing the effects of lymphocytes on cancer cell growth and motility
- Chemotherapy for tumors: An analysis of the dynamics and a study of quadratic and linear optimal controls
- Stability and bifurcation analysis of a mathematical model for tumor-immune interaction with piecewise constant arguments of delay
- Cost-effectiveness analysis of optimal strategy for tumor treatment
- A simple model of tumor-immune interaction: the effect of antigen delay
- Dynamics aspects and bifurcations of a tumor-immune system interaction under stationary immunotherapy
- Periodic and chaotic oscillations in a tumor and immune system interaction model with three delays
- A study of behaviour for immune and tumor cells in immunogenetic tumour model with non-singular fractional derivative
This page was built for publication: Behavior of tumors under nonstationary therapy
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q1867933)