Does tumor growth follow a ``universal law?
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Publication:2177407
DOI10.1016/S0022-5193(03)00221-2zbMATH Open1464.92065arXivphysics/0303050WikidataQ47426728 ScholiaQ47426728MaRDI QIDQ2177407FDOQ2177407
Authors: Caterina Guiot, Piero Giorgio Degiorgis, Pier P. Delsanto, Pietro Gabriele, Thomas S. Deisboeck
Publication date: 6 May 2020
Published in: Journal of Theoretical Biology (Search for Journal in Brave)
Abstract: A general model for the ontogenetic growth of living organisms has been recently proposed. Here we investigate the extension of this model to the growth of solid malignant tumors. A variety of in vitro and in vivo data are analyzed and compared with the prediction of a 'universal' law, relating properly rescaled tumor masses and tumor growth times. The results support the notion that tumor growth follows such a universal law. Several important implications of this finding are discussed, including its relevance for tumor metastasis and recurrence, cell turnover rates, angiogenesis and invasion.
Full work available at URL: https://arxiv.org/abs/physics/0303050
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