Local controllability and optimal control for a model of combined anticancer therapy with control delays
DOI10.3934/MBE.2017013zbMATH Open1351.93018OpenAlexW2530601300WikidataQ50544120 ScholiaQ50544120MaRDI QIDQ335260FDOQ335260
Authors: Jerzy Klamka, Helmut Maurer, Andrzej Świerniak
Publication date: 2 November 2016
Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.3934/mbe.2017013
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discretizationnonlinear programmingoptimal controloptimality conditionscombined cancer therapycontrol delayslocal controllability
Numerical mathematical programming methods (65K05) Numerical optimization and variational techniques (65K10) Medical applications (general) (92C50) Dynamical systems in biology (37N25) Nonlinear programming (90C30) Numerical methods based on nonlinear programming (49M37) Controllability (93B05) Existence theories for optimal control problems involving ordinary differential equations (49J15) Optimality conditions for problems involving ordinary differential equations (49K15) Discrete approximations in optimal control (49M25) Applications of optimal control and differential games (49N90) Control/observation systems governed by ordinary differential equations (93C15)
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Cited In (6)
- Local controllability of models of combined anticancer therapy with delays in control
- Controllability of a model of combined anticancer therapy
- Modeling of tumor growth incorporating the effects of necrosis and the effect of Bevacizumab
- Closed-loop control of tumor growth by means of anti-angiogenic administration
- Optimal control of a delayed HIV model
- Optimal control problems with time delays: two case studies in biomedicine
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