Some Alternatives to Asymptotic Tests for the Analysis of Pharmacogenetic Data Using Nonlinear Mixed Effects Models

DOI10.1111/j.1541-0420.2011.01665.xzbMath1241.62148OpenAlexW2125121971WikidataQ34065965 ScholiaQ34065965MaRDI QIDQ2894000

Marylore Chenel, France Mentré, Julie Bertrand, Emmanuelle Comets

Publication date: 27 June 2012

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.1541-0420.2011.01665.x

zbMATH Keywords

permutation testsnonlinear mixed effects modelsfirst-order approximation\(F\)-distribution-based approach

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Stochastic approximation (62L20)

Related Items

Approximate testing in two-stage nonlinear mixed models, Approximate Small-Sample Tests of Fixed Effects in Nonlinear Mixed Models

Cites Work

• Unnamed Item
• Seemingly unrelated nonlinear regressions
• Permutation tests. A practical guide to resampling methods for testing hypotheses
• Linear mixed models in practice: a SAS-oriented approach
• P-values from permutation and F-tests
• Proceedings of the second Seattle symposium in biostatistics. Analysis of correlated data, Seattle, WA, USA, November 20--21, 2000.
• Statistical tools for nonlinear regression. A practical guide with S-PLUS examples
• Approximate F-tests of multiple degree of freedom hypotheses in generalized least squares analyses of unbalanced split-plot experiments
• Small Sample Inference for Fixed Effects from Restricted Maximum Likelihood
• Assessing antiviral potency of anti-HIV therapies in vivo by comparing viral decay rates in viral dynamic models
• Mixed-Effects Models in S and S-PLUS
• The Effective Sample Size and an Alternative Small-Sample Degrees-of-Freedom Method