On the calculation of bone pore water pressure due to mechanical loading (Q1282783)

We calculate the bone fluid pressure in the lacunar-canalicular porosity of the cortical bone matrix induced by functional mechanical loading and compare it with that induced by the blood pressure differences. This problem reduces to the problem of determining the bone fluid pressure in a representative axially compressed osteon, which is approximately an annular cylindrical structure. Two available poroelastic approximations, a beam analogy model and a single osteon model, are compared and discussed.