Adaptive Dc-optimal designs for dose finding based on a continuous efficacy endpoint

DOI10.1002/BIMJ.200900214zbMath1208.62116OpenAlexW2094756353WikidataQ85125696 ScholiaQ85125696MaRDI QIDQ3076087

Vladimir Dragalin, S. Krishna Padmanabhan

Publication date: 17 February 2011

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.200900214

zbMATH Keywords

response modeladaptive designsigmoid \(E_{\max}\) modeltarget dose estimation

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

Related Items (4)

A comparison of allocation strategies for optimising clinical trial designs under variance heterogeneity ⋮ On the combination of c‐ and D‐optimal designs: General approaches and applications in dose–response studies ⋮ Optimal dose‐finding for efficacy–safety models ⋮ On optimal designs for clinical trials: an updated review

Cites Work

• Unnamed Item
• Sequential Methods in Multi-Arm Clinical Trials
• Optimal Designs for Dose-Finding Studies
• On the Equivalence of Constrained and Compound Optimal Designs
• Combining Multiple Comparisons and Modeling Techniques in Dose‐Response Studies

This page was built for publication: Adaptive Dc-optimal designs for dose finding based on a continuous efficacy endpoint