Phase resetting in medicine and biology. Stochastic modelling and data analysis (Q1305141)

This book is devoted to the intriguing problem of the complex dynamics of coupled oscillators in neuroactivity. The book is not for the unprepared reader -- the theory of Winfree on phase resetting and Haken's synergetics theory form the foundations of this monography. The author develops a stochastic approach to phase resetting of a population of interacting oscillators in the presence of noise. The results of the study can be applied to different branches of natural sciences but its motivation comes from neurophysiological considerations and all results in the book are interpreted in terms of neuroscience. Further, data analysis methods are developed to make possible the use of theoretical results of stimulation induced transient dynamics in electroencephalography and magnetoencephalography data sets. Finally, neurologists and neurosurgeons may find it useful to learn about a new stimulation mode, namely a single pulse deep brain stimulation with feedback control suggested for the treatment of Parkinsonian resting tremor in patients with chronically implanted electrodes.