Interval estimation for drop-the-losers designs

DOI10.1093/biomet/asq003zbMath1406.62087OpenAlexW1975735320MaRDI QIDQ3585403

Weizhen Wang, Samuel S. Wu, Mark C. K. Yang

Publication date: 19 August 2010

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biomet/asq003

zbMATH Keywords

clinical trialadaptive designtwo-stage test\(p\)-value combinationdrop-the-losers design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Design of statistical experiments (62K99)

Related Items (6)

Admissible and minimax estimation of the parameters of the selected normal population in two-stage adaptive designs under reflected normal loss function ⋮ On estimating the mean of the selected normal population in two-stage adaptive designs ⋮ Conditionally unbiased and near unbiased estimation of the selected treatment mean for multistage drop‐the‐losers trials ⋮ Confidence intervals for confirmatory adaptive two‐stage designs with treatment selection ⋮ Confidence intervals for the selected population in randomized trials that adapt the population enrolled ⋮ A comparison of methods for constructing confidence intervals after phase II/III clinical trials

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