Confidence intervals for confirmatory adaptive two-stage designs with treatment selection
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Recommendations
- Likelihood inference for a two-stage design with treatment selection
- Test-compatible confidence intervals for adaptive two-stage single-arm designs with binary endpoint
- Adaptive confidence intervals of desired length and power for normal means
- Point estimates and confidence regions for sequential trials involving selection
- Exact confidence limits for the probability of response in two-stage designs
Cites work
- Accurate parametric inference for small samples
- Closed Testing Procedures for Group Sequential Clinical Trials with Multiple Endpoints
- Drop-the-losers design: binomial case
- Estimation following selection of the largest of two normal means
- Evaluation of Experiments with Adaptive Interim Analyses
- Impacts on type I error rate with inappropriate use of learn and confirm in confirmatory adaptive design trials
- Interval estimation for drop-the-losers designs
- Likelihood inference for a two-stage design with treatment selection
- Monitoring Pairwise Comparisons in Multi-Armed Clinical Trials
- Phase 2 and 3 Combination Designs to Accelerate Drug Development
- Point estimates and confidence regions for sequential trials involving selection
- Recursive Combination Tests
- Two stage conditionally unbiased estimators of the selected mean
Cited in
(16)- Exact confidence limits for the probability of response in two-stage designs
- Likelihood inference for a two-stage design with treatment selection
- Sequential and two-stage fixed-width confidence interval estimation in response-adaptive designs
- Adjusting for selection bias in assessing treatment effect estimates from multiple subgroups
- Adaptive confidence intervals of desired length and power for normal means
- Point estimates and confidence regions for sequential trials involving selection
- Point estimation for adaptive trial designs. I: A methodological review
- Test-compatible confidence intervals for adaptive two-stage single-arm designs with binary endpoint
- Conditional Estimation in Two-Stage Adaptive Designs
- Fixed-width confidence interval for two-stage response-adaptive designs in ridit analysis
- On confidence bounds for the Bauer-Köhne two-stage test
- A class of confidence intervals for sequential phase II clinical trials with binary outcome
- Confidence intervals for the selected population in randomized trials that adapt the population enrolled
- Simultaneous confidence intervals that are compatible with closed testing in adaptive designs
- A comparison of methods for constructing confidence intervals after phase II/III clinical trials
- Maximum type 1 error rate inflation in multiarmed clinical trials with adaptive interim sample size modifications
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