Impacts on type I error rate with inappropriate use of learn and confirm in confirmatory adaptive design trials

DOI10.1002/BIMJ.200900207zbMath1208.62176OpenAlexW2028249078WikidataQ45778475 ScholiaQ45778475MaRDI QIDQ3076083

Sue-Jane Wang, H. M. James Hung, R. T. O'Neill

Publication date: 17 February 2011

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.200900207

zbMATH Keywords

learning free type I error ratestudywise type I error rate

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Related Items (2)

Confidence intervals for confirmatory adaptive two‐stage designs with treatment selection ⋮ Multiple comparisons in complex clinical trial designs

Cites Work

• A review of phase 2-3 clinical trial designs
• Modification of Sample Size in Group Sequential Clinical Trials

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