Impacts on type I error rate with inappropriate use of learn and confirm in confirmatory adaptive design trials

DOI10.1002/BIMJ.200900207MaRDI QIDQ3076083zbMATH OpenOpenAlexWikidataFDO

Authors Sue-Jane Wang, H. M. James Hung, R. T. O'Neill

Publication date 17 February 2011

Published in Biometrical Journal (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/bimj.200900207

zbMATH Keywords

learning free type I error ratestudywise type I error rate

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Recommendations

• Probabilistic foundation of confirmatory adaptive designs
• Confirmatory clinical trials with an adaptive design
• Sequential methods in multi-arm clinical trials
• On design and inference for two-stage adaptive clinical trials with dependent data
• A Calculus for Design of Two-Stage Adaptive Procedures

Cites work

• A review of phase 2-3 clinical trial designs
• Modification of Sample Size in Group Sequential Clinical Trials

Cited in

(5)

• Multiple comparisons in complex clinical trial designs
• On the efficiency of adaptive sample size design
• Adaptive dose-finding: Proof of concept with type I error control
• Confidence intervals for confirmatory adaptive two-stage designs with treatment selection
• Probabilistic foundation of confirmatory adaptive designs

This page was built for publication: Impacts on type I error rate with inappropriate use of learn and confirm in confirmatory adaptive design trials

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3076083)