Multiple comparisons in complex clinical trial designs

DOI10.1002/bimj.201200048zbMath1441.62374OpenAlexW1533003280WikidataQ38101915 ScholiaQ38101915MaRDI QIDQ4921957

H. M. James Hung, Sue-Jane Wang

Publication date: 28 May 2013

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201200048

zbMATH Keywords

replicationstrong controlinterim analysisgroup sequentialstrength of evidenceevidence-settingexperiment-wisestudy-wise

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Paired and multiple comparisons; multiple testing (62J15)

Cites Work

• Graphical approaches for multiple comparison procedures using weighted Bonferroni, Simes, or parametric tests
• Testing for Efficacy in Primary and Secondary Endpoints by Partitioning Decision Paths
• Testing a Primary and a Secondary Endpoint in a Group Sequential Design
• Challenges to multiple testing in clinical trials
• Impacts on type I error rate with inappropriate use of learn and confirm in confirmatory adaptive design trials
• Testing Whether an Identified Treatment Is Best
• A Multiple Comparison Procedure for Comparing Several Treatments with a Control
• Discrete Sequential Boundaries for Clinical Trials
• A sharper Bonferroni procedure for multiple tests of significance

This page was built for publication: Multiple comparisons in complex clinical trial designs