On Testing an Unspecified Function Through a Linear Mixed Effects Model with Multiple Variance Components

DOI10.1111/j.1541-0420.2012.01790.xzbMath1259.62035OpenAlexW2094672644WikidataQ36503959 ScholiaQ36503959MaRDI QIDQ4911936

Yuanjia Wang, Huaihou Chen

Publication date: 20 March 2013

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3535528

zbMATH Keywords

likelihood ratio testpenalized splinesgenome-wide association studygeneralized \(F\)-testtest variance components

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Numerical computation using splines (65D07) Linear regression; mixed models (62J05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Related Items

A Marginal Approach to Reduced-Rank Penalized Spline Smoothing With Application to Multilevel Functional Data, Testing for additivity in non‐parametric regression, Restricted likelihood ratio tests for linearity in scalar-on-function regression

Uses Software

• R
• nlme
• SemiPar

Cites Work

• Unnamed Item
• Size and power of tests for a zero random effect variance or polynomial regression in additive and linear mixed models
• Flexible smoothing with \(B\)-splines and penalties. With comments and a rejoinder by the authors
• Smoothing and mixed models
• Counting degrees of freedom in hierarchical and other richly-parameterised models
• ON SEMIPARAMETRIC REGRESSION WITH O'SULLIVAN PENALIZED SPLINES
• Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests Under Nonstandard Conditions
• Degrees-of-freedom tests for smoothing splines
• Semiparametric Regression
• Likelihood Ratio Tests in Linear Mixed Models with One Variance Component
• Variance Components Testing in the Longitudinal Mixed Effects Model
• Exact likelihood ratio tests for penalised splines
• Conditional Akaike information for mixed-effects models