Model-free approach to quantifying the proportion of treatment effect explained by a surrogate marker

DOI10.1093/BIOMET/ASZ065zbMath1435.62402OpenAlexW2997938744WikidataQ96686105 ScholiaQ96686105MaRDI QIDQ5222223

Tianxi Cai, L. Tian, Layla Parast, Xu An Wang

Publication date: 1 April 2020

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc7315285

zbMATH Keywords

nonparametric estimationrandomized clinical trialsurrogate markerproportion of treatment effect explained

Mathematics Subject Classification ID

Density estimation (62G07) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sampling theory, sample surveys (62D05)

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Evaluating multiple surrogate markers with censored data ⋮ Quantifying direct and indirect effect for longitudinal mediator and survival outcome using joint modeling approach ⋮ Robust Approach to Combining Multiple Markers to Improve Surrogacy ⋮ Testing for Heterogeneity in the Utility of a Surrogate Marker

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